Back to the list
Congress: ECR25
Poster Number: C-27065
Type: Poster: EPOS Radiologist (educational)
DOI: 10.26044/ecr2025/C-27065
Authorblock: H. M. Chang, D. Vanniasegaram, J. V. Cook, V. Gnanananthan; London/UK
Disclosures:
Hanna Mari Chang: Nothing to disclose
Divyen Vanniasegaram: Nothing to disclose
Jane Valmai Cook: Nothing to disclose
Visvalingam Gnanananthan: Nothing to disclose
Keywords: Bones, Musculoskeletal bone, Musculoskeletal spine, Absorptiometry / Bone densitometry, CT, Technology assessment, Arteriosclerosis, Demineralisation-Bone, Osteoporosis
Learning objectives Learning objectives Understand the key factors contributing to bone strength. Evaluate the role of TBS in fracture risk prediction and patient management. Assess the impact of peridiscal sclerosis, scoliosis and atherosclerosis on TBS. Investigate the correlation between trabecular bone score (TBS) and CT Hounsfield Units (HU) of the lumbar spine.
Read more Background BackgroundBone strength and osteoporotic fracture riskBone mineral density (BMD) and trabecular microarchitecture are key determinants of bone strength. Most fragility fractures occur in individuals with normal BMD or osteopenia, highlighting the limitations of relying on BMD alone in predicting fracture risk[1]. [fig 1] Osteoporotic fractures pose significant morbidity, mortality and healthcare costs. Comprehensive and accurate assessment of bone strength is therefore a public health priority. Early diagnosis, prevention and prompt treatment of individuals at risk of osteoporotic fractures are key. DEXA and TBSDual-energy X-ray...
Read more Findings and procedure details FindingsTBS and bone protection treatment16% (n=16/99) had degraded microarchitecture on TBS despite having normal or osteopenic BMD on DEXA. These findings suggest that TBS identifies an additional cohort of patients who could potentially benefit from bone protection treatment, despite not reaching treatment threshold with DEXA T-score alone. TBS and CT Hounsfield UnitsThere is a positive correlation between TBS and CT HUs of lumbar vertebrae (r=0.39, p<0.001). CT is a readily available imaging modality that offers an alternative approach to assess bone...
Read more Conclusion ConclusionTBS has an emerging role for improving osteoporotic fracture risk prediction by assessing bone trabecular microarchitecture. TBS identifies an additional group of patients who may benefit from bone protection treatment compared to DEXA alone. Peridiscal sclerosis, scoliosis and atherosclerosis are common findings in patients undergoing DEXA, but do not significantly affect TBS.
Read more References Johnell O, Kanis JA, Oden A, Johansson H, De Laet C, Delmas P, et al. Predictive Value of BMD for Hip and Other Fractures. Journal of Bone and Mineral Research. 2005 Jul 1;20(7):1185–94. Shevroja E, Reginster JY, Lamy O, Al-Daghri N, Chandran M, Demoux-Baiada AL, et al. Update on the clinical use of trabecular bone score (TBS) in the management of osteoporosis: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis...
Read more
GALLERY