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Congress: ECR26
Poster Number: C-18872
Type: Poster: EPOS Radiologist (educational)
Authorblock: S. Reddy K1, S. R. Kankara1, D. Jayanna1, U. Nayak1, Y. Aswani2, S. Sharma1, S. Ahmed1, S. K. Deepalam1, A. R. Gangwani1; 1Bangalore/IN, 2Iowa City/US
Disclosures:
Shravan Reddy K: Nothing to disclose
Shreyas Reddy Kankara: Nothing to disclose
Dhanush Jayanna: Nothing to disclose
Unnathi Nayak: Nothing to disclose
Yashant Aswani: Nothing to disclose
Shikha Sharma: Nothing to disclose
Sabha Ahmed: Nothing to disclose
Sai Kanth Deepalam: Nothing to disclose
Alisha Rajesh Gangwani: Nothing to disclose
Keywords: CNS, Head and neck, Thorax, CT, MR, Ultrasound, Imaging sequences, Infection
Learning objectives To review the characteristic multimodality imaging features of mucormycosis across multiple organ systems, including rhino-orbito-cerebral, pulmonary, gastrointestinal, solid organ, and cutaneous involvement, while highlighting less common manifestations at unusual sites. This exhibit demonstrates how imaging enables accurate assessment of disease extent and complications, facilitating timely diagnosis and appropriate management in high-risk, immunocompromised patients.
Read more Background Mucormycosis is a rapidly progressive, angioinvasive fungal infection caused by organisms of the order Mucorales, most commonly Rhizopus and Mucor. It predominantly affects immunocompromised patients, with major risk factors including uncontrolled diabetes mellitus, hematologic malignancy, stem cell or solid organ transplantation, prolonged neutropenia, corticosteroid therapy, and deferoxamine use.Infection follows inhalation, ingestion, or direct inoculation of fungal spores. Marked angioinvasion leads to vascular thrombosis, tissue ischemia, and necrosis, with rapid spread along vascular, neural, and contiguous tissue planes, accounting for the...
Read more Findings and procedure details Mucormycosis demonstrates a wide imaging spectrum depending on the site of involvement, with clinical manifestations closely paralleling disease extent. At selected unusual sites of involvement, radiologic findings were confirmed by histopathological examination, establishing the diagnosis of mucormycosis.Rhino-orbito-cerebral mucormycosisRhino-orbito-cerebral mucormycosis (ROCM) is the most common form of mucormycosis. Infection typically originates in the nasal cavity or paranasal sinuses following inhalation of spores and rapidly progresses via direct extension through osseous structures, skull base foramina, and along vascular and neural pathways, leading...
Read more Conclusion Mucormycosis presents with a wide and often overlapping spectrum of imaging findings across multiple organ systems, frequently mimicking other infectious or inflammatory conditions. Recognition of characteristic abnormalities and patterns of invasive spread, particularly in high-risk immunocompromised patients, is essential for early diagnosis and delineation of disease extent. Timely radiologic identification directly influences clinical decision-making, surgical planning, and antifungal therapy, underscoring the radiologist’s central role in improving outcomes in this frequently fatal infection.
Read more References Kurokawa M, Kurokawa R, Baba A, Kim J, Tournade C, Mchugh J, et al. Deadly Fungi: Invasive Fungal Rhinosinusitis in the Head and Neck. RadioGraphics. 2022 Nov;42(7):220059. Safder S, Carpenter JS, Roberts TD, Bailey N. The “Black Turbinate” Sign: An Early MR Imaging Finding of Nasal Mucormycosis. American Journal of Neuroradiology. 2010 Apr 1;31(4):771–4. Deshmukh YA, Vaid S, Chandorkar A, Atre A, Patil S. Imaging spectrum of rhino-orbital-cerebral mucormycosis secondary to COVID-19 infection: a reporting checklist. Pol J Radiol. 2022 June 22;87:e333–47. Chikley...
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