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Congress: ECR25
Poster Number: C-25058
Type: Poster: EPOS Radiologist (educational)
Authorblock: D. A. Zambrano, M. R. López De La Torre Carretero, C. Mbongo, A. M. Delgado Brito, P. Del Nido Recio, A. Ezponda Casajus; Pamplona/ES
Disclosures:
Daniel Alfonso Zambrano: Nothing to disclose
Manuel Rafael López De La Torre Carretero: Nothing to disclose
Carmen Mbongo: Nothing to disclose
Adolfo Manuel Delgado Brito: Nothing to disclose
Pablo Del Nido Recio: Nothing to disclose
Ana Ezponda Casajus: Nothing to disclose
Keywords: Cardiac, Neuroradiology brain, Thorax, CT, MR, Contrast agent-intravenous, Connective tissue disorders, Inflammation
Learning objectives Understand sarcoidosis as a systemic granulomatous disease with unknown etiology. Identify typical and atypical imaging findings across various systems. Recognize sarcoidosis-like reactions from immunotherapies and differentiate them from true sarcoidosis. Discuss the role of advanced imaging techniques like cardiac MRI and PET-CT.
Read more Background Sarcoidosis is characterized by non-caseating granulomas, primarily affecting the lungs and other organs. Imaging is crucial for diagnosis, with CT, MRI, and PET-CT revealing characteristic findings. Sarcoidosis-like reactions from immune checkpoint inhibitors can mimic sarcoidosis, creating diagnostic challenges. This poster reviews cases of diverse radiological manifestations of sarcoidosis and sarcoidosis-like syndromes.
Read more Findings and procedure details IntroductionSarcoidosis is a multisystemic granulomatous disease of unknown etiology, characterized by the formation of non-caseating granulomas in various organs [1,2]. Although it can affect virtually any organ, pulmonary involvement and thoracic lymphadenopathy are predominant, with abnormalities observed on chest radiographs in more than 90% of patients with thoracic sarcoidosis [1,3]. In radiology, high-resolution computed tomography (HRCT) is superior to chest radiographs for assessing the extent of the disease [3,4]. Typical HRCT findings include micronodules with perilymphatic and broncho-centric distribution, perihilar...
Read more Conclusion Sarcoidosis is a systemic granulomatous disease that can affect multiple organ systems, leading to a wide range of radiologic manifestations. High-resolution CT (HRCT) is particularly useful in evaluating pulmonary involvement, revealing findings such as perilymphatic nodules, bronchovascular bundle thickening, and fibrosis. MRI is valuable in assessing cardiac and central nervous system involvement, providing detailed tissue characterization. PET/CT with fluorodeoxyglucose (FDG) is effective in detecting active inflammatory sites and assessing the extent of systemic involvement. These imaging modalities are essential for...
Read more References Ganeshan D, Menias CO, Lubner MG, et al. Sarcoidosis from head to toe: What the radiologist needs to know. Radiographics. 2018;38(4):1180-1200. https://doi.org/10.1148/rg.2018170157 Shaikh F, Abtin FG, Lau R, et al. Radiographic and histopathologic features in sarcoidosis: A pictorial display. Semin Respir Crit Care Med. 2020;41(5):758-784. https://doi.org/10.1055/s-0040-1712534 Silva M, Nunes H, Valeyre D, Sverzellati N. Imaging of sarcoidosis. Clin Rev Allergy Immunol. 2015;49(1):45-53. https://doi.org/10.1007/s12016-015-8478-7 Akaike G, Itani M, Shah H, et al. PET/CT in the diagnosis and workup of sarcoidosis: Focus on atypical manifestations....
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