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Congress: ECR24
Poster Number: C-14130
Type: EPOS Radiologist (scientific)
DOI: 10.26044/ecr2024/C-14130
Authorblock: C. Boldrini, S. Amodeo, R. Dattoli, A. Marra, P. Belli; Roma/IT
Disclosures:
Cristiana Boldrini: Nothing to disclose
Silvia Amodeo: Nothing to disclose
Roberta Dattoli: Nothing to disclose
Angelica Marra: Nothing to disclose
Paolo Belli: Nothing to disclose
Keywords: Breast, CT, MR, PET, Diagnostic procedure, Cancer
Purpose The normal pattern of nipple enhancement at magnetic resonance (MR) is defined on the basis of healthy individuals, since it correlates with the structural anatomy of the nipple. Understanding the normal range of nipple morphology and nipple enhancement at MR enables radiologists to better detect abnormalities. Nipple morphology refers to the configuration of the nipple as defined on the basis of its outer contour, which is described as everted, flat, or inverted and best assessed on magnetic resonance MIP images [1]. Nipple...
Read more Methods and materials Our study considered fourteen (14) patients with breast tumor which showed infiltration of the NAC; the patients were all candidates to neoadjuvant chemotherapy, thus they underwent MR, CT and PET/CT. We distinguished the pattern of enhancement at MR on the basis of the morphology and intensity. There were three types of morphology: SLE (smooth superficial enhancement) at the level of the skin, NEZ (zone without enhancement immediately below the SLE), INE (enhancement of the nipple below the NEZ but above the...
Read more Results  Observational findings The nipple morphology is most frequently everted (9 cases, 64,3%), less commonly flat (3 cases, 21,4%), and occasionally inverted (2 cases, 14,3%). Areolar and periareolar thickening of the skin occurs in 5 cases (35,7%) of the examined population. At MR, pathological nipples most commonly demonstrate SLE (57,1%) overlying a NEZ (50%), deep to which there is patchy (85,7%) or linear (14,3%) INE. INE appears to be the most common pattern of enhancement of tumor-infiltrated NAC (Figure 4, 5, 6)....
Read more Conclusion In our population, the most represented pattern of MR enhancement was INE (100%), with patchy INE being the most frequent. At CT scans, enhancement of the NAC was detectable in almost all of them (93%), affecting principally the base and the body together (71%).Even if the pathological involvement of the NAC can not always be assessed in the surgical specimen, MRI and PET-CT with SUV measurement can provide precious information about the tumor-infiltrated nipple; in our population, the average value...
Read more References [1] Gao Y, Brachtel EF, Hernandez O, Heller SL. An Analysis of Nipple Enhancement at Breast MRI with Radiologic-Pathologic Correlation. Radiographics. 2019 Jan-Feb;39(1):10-27. doi: 10.1148/rg.2019180039. Epub 2018 Dec 14.[2] Bae SJ, Cha YJ, Eun NL, Ji JH, Kim D, Lee J, Ahn SG, Son EJ, Jeong J. Diagnostic Accuracy of Nonmass Enhancement at Breast MRI in Predicting Tumor Involvement of the Nipple: A Prospective Study in a Single Institution. Radiology. 2021 Oct;301(1):47-56. doi: 10.1148/radiol.2021204136. Epub 2021 Jul 13.[3] Agarwal S,...
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