In our population, the most represented pattern of MR enhancement was INE (100%), with patchy INE being the most frequent. At CT scans, enhancement of the NAC was detectable in almost all of them (93%), affecting principally the base and the body together (71%).

Even if the pathological involvement of the NAC can not always be assessed in the surgical specimen, MRI and PET-CT with SUV measurement can provide precious information about the tumor-infiltrated nipple; in our population, the average value of SUV of pathologic NACs is 3,84, while the average value of SUV of contralateral normal NACs is 2,25. The average NAC-SUV ratio is 1,7, which means that pathological NAC has the largest SUV value of about one and a half times. CT images have less sensitivity compared to MR in the detection of SLE (observed in patients with nipple thickening).

A standardized language is desirable in the ACR BIRADS ® in order to avoid mistakes and improve the understanding among radiologists.