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Congress: ECR25
Poster Number: C-15594
Type: Poster: EPOS Radiologist (educational)
DOI: 10.26044/ecr2025/C-15594
Authorblock: C. Wiehoff Melián, S. D. Duque Yemail, S. Rodríguez Pérez, J. Nuñez Talavera, C. R. Hernández Socorro; Las Palmas de Gran Canaria/ES
Disclosures:
Carlos Wiehoff Melián: Nothing to disclose
Sebastián Duque Duque Yemail: Nothing to disclose
Saray Rodríguez Pérez: Nothing to disclose
Jorge Nuñez Talavera: Nothing to disclose
Carmen Rosa Hernández Socorro: Nothing to disclose
Keywords: Neuroradiology brain, MR, Education, Cancer, Lymphoma, Metastases
Learning objectives This study presents a bibliographic review of the findings described in the scientific literature that aid in the differentiation or initial approach to a single, solid, supratentorial brain lesion enhanced with gadolinium.
Read more Background Glioblastoma, metastases, and lymphoma are the most common intracranial tumors in adults.The differential diagnosis between them can pose a significant imaging challenge due to their highly variable radiological presentation and the overlapping imaging characteristics they present.Accurately distinguishing these tumors and guiding physicians toward the correct diagnosis is crucial, as it directly impacts therapeutic decision-making and, consequently, can positively influence the patient's prognosis.This bibliographic review examines the MRI characteristics of each of the three pathologies, primarily focusing on the infiltrative nature...
Read more Findings and procedure details Criteria to Analyze by Sequence:T1 and T1 Gd(+): Morphological CriteriaT2: Edema-lesion relationship; Signal intensityFLAIR: Cortical infiltrationDiffusion (DWI/ADC): ADC valuesMagnetic Susceptibility (SWI): Relation with medullary veins; Intratumoral susceptibility signal (ITSS)Perfusion (RM DSC/DCE): Relative cerebral blood volume (rCBV); Percentage of signal recovery (PSR) T1 GD (+)Glioblastoma:Primary central nervous system tumorTypically irregular shape with poorly defined marginsPresence of necrosisMetastases:Secondary tumor (hematogenous spread)Solitary lesion in 50% of cases; if multiple, metastasis should be the primary considerationGenerally located at the cortico-subcortical junctionAlmost spherical shape with well-defined...
Read more Conclusion A solitary space-occupying lesion in the brain parenchyma represents a daily diagnostic challenge for radiologists. With continuous advancements and increased accessibility to imaging studies, the radiologist's role has become increasingly important in determining diagnostic, therapeutic, and prognostic possibilities. By utilizing various imaging parameters, radiologists can achieve a more accurate diagnosis even before histological evaluation.
Read more References  Chen XZ, Yin XM, Ai L, Chen Q, Li SW, Dai JP. Diferenciación entre glioblastoma multiforme cerebral y metástasis solitaria: análisis cualitativo y cuantitativo basado en imágenes de resonancia magnética de rutina. American Journal of Neuroradiology. 28 de junio de 2012;33(10):1907–12. doi:10.3174/ajnr.a3106  MUCCIO CF, TEDESCHI E, UGGA L, CUOCOLO R, ESPOSITO G, CARANCI F. Metástasis cerebrales solitarias frente a gliomas de alto grado: utilidad de dos signos de resonancia magnética en el diagnóstico diferencial. Anticancer Research. 2019 Sept;39(9):4905–9. doi:10.21873/anticanres.13677 Stuckey S, Wijedeera...
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