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Congress: ECR25
Poster Number: C-11911
Type: Poster: EPOS Radiologist (scientific)
Authorblock: O. E. Tarı, R. Göçmen; Ankara/TR
Disclosures:
Onur Ege Tarı: Nothing to disclose
Rahşan Göçmen: Nothing to disclose
Keywords: Neuroradiology brain, MR, MR-Diffusion/Perfusion, PET-CT, Comparative studies, Diagnostic procedure, Outcomes analysis, Infection, Inflammation
Purpose Acute cerebellitis (AC) is a clinico-radiological syndrome which the keystone element is inflammation of the cerebellum. It can be acute or subacute and is consisted of both cerebellar dysfunction and radiological evidence of inflammatory swelling. It is a children’s disease and typically a benign, self-limited process. While the exact pathogenesis remains unclear, this entity is primarily associated with infectious, post-infectious and autoimmune mechanisms in children. While AC has been well-characterized in children, limited case reports and a lack of dedicated...
Read more Methods and materials This single-center retrospective study included all patients over 18 and admitted to our tertiary referral hospital between January 2010 and June 2024. Study patients had to meet the following inclusion criteria: presentation with symptoms compatible with acute/subacute cerebellar syndrome (e.g., ataxia, dysarthria, or nystagmus) or signs of inflammation on brain MRI. Patient demographics, clinical presentations, laboratory and imaging results, etiological diagnoses, treatment approaches, and outcomes were recorded.The MRI studies were performed on 1.5T or 3S.0T scanners. All but one patient...
Read more Results A total of 16 patients were included in the study.  The mean age of the patients was 39.4 years (range: 19–83 years), with 62.5% of the patients being female. The most frequent symptoms experienced by the patients were altered consciousness (n=12, 75%), dysarthria (n=9, 56%), ataxia (n=9, 56%), vomiting (n=7, 44%), and fever (n=7, 44%). Less common symptoms included seizures (n=5, 31%) and headaches (n=5, 31%).  Most patients (75%, n=12) experienced an acute onset of symptoms within 14 days, with...
Read more Conclusion Adult-onset cerebellitis differs significantly from its pediatric form. In adults, post-infectious causes are less common, with paraneoplastic and infectious origins being more prevalent. Additionally, cerebellitis can sometimes be the first sign of an undiagnosed malignancy. Unlike the acute onset often seen in children, adults may experience a more gradual progression of symptoms. The prognosis is generally poorer in adults, highlighting the critical need for prompt diagnosis and treatment to improve patient outcomes.
Read more References Poretti A, Benson JE, Huisman TA, Boltshauser E. Acute ataxia in children: approach to clinical presentation and role of additional investigations. Neuropediatrics. 2013;44(3):127-41. doi: 10.1055/s-0032-1329909. Lancella L, Esposito S, Galli ML, Bozzola E, Labalestra V, Boccuzzi E, et al. Acute cerebellitis in children: an eleven year retrospective multicentric study in Italy. Ital J Pediatr. 2017;43(1):54. doi: 10.1186/s13052-017-0370-z. Emelifeonwu JA, Shetty J, Kaliaperumal C, Gallo P, Sokol D, Soleiman H, et al. Acute Cerebellitis in Children: A Variable Clinical Entity. J Child Neurol....
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