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Congress: ECR25
Poster Number: C-27813
Type: Poster: EPOS Radiologist (scientific)
DOI: 10.26044/ecr2025/C-27813
Authorblock: S. El Graini, S. Cherkaoui, H. Retal, I. Dokal, Y. Omor, R. Latib, S. Amalik; Rabat/MA
Disclosures:
Soumya El Graini: Nothing to disclose
Sara Cherkaoui: Nothing to disclose
Hamza Retal: Nothing to disclose
Ibrahima Dokal: Nothing to disclose
Youssef Omor: Nothing to disclose
Rachida Latib: Nothing to disclose
Sanae Amalik: Nothing to disclose
Keywords: Oncology, MR, Diagnostic procedure, Metastases
Purpose Determine the epidemiological characteristics of NSCLC brain metastases in our institution. Recognize the various imaging characteristics of NSCLC brain metastases. Emphasize the role of advanced imaging techniques in monitoring treated NSCLC brain metastases.
Read more Methods and materials This retrospective descriptive study was conducted from January 2022 to December 2024, focusing on patients with brain metastases (BM) from NSCLC, presented with various characteristics and locations. Morphological imaging was used to assess the metastases' number, location, size, and shape. When advanced imaging sequences were available, they allowed for the evaluation of tumor cellularity (diffusion sequence), tumor vascularization (PWI), and metabolic profiles (MRS).A. CT Scan Protocol Patient Positioning: Supine, arms alongside the body. Scout View: From the vertex to C2. Slice Thickness: <1...
Read more Results I. RESULTS Epidemiological Characteristics of NSCLC Brain Metastases in Our Institution Among 80 suspected cases of brain metastases, 74 patients were confirmed to have brain involvement, of which 67 had NSCLC. Histological Subtypes: 57 adenocarcinomas (ADK) 5 squamous cell carcinomas (SCC) 2 sarcomatoid carcinomas 2 non-specified NSCLC 1 missing data Demographics: Mean age: 62.3 years Male: 55, Female: 12 Strong smoking association Mode of Metastasis Detection: Systematic extension workup in known lung cancer cases. Neurological symptoms such as headaches, visual disturbances, gait abnormalities, balance disorders, focal neurological deficits, or signs of intracranial hypertension. Incidentally detected...
Read more Conclusion Multimodal MRI, particularly perfusion and spectroscopy sequences, is an essential tool for diagnosing and differentiating brain metastases from NSCLC. Furthermore, it aids in treatment planning and therapeutic monitoring, thereby facilitating more effective patient management.
Read more References Peters S, Camidge DR, Shaw AT, et al. Alectinib versus crizotinib in untreated ALK-positive non-small-cell lung cancer. N Engl J Med. 2017, 377:829-38. doi: 10.1056/NEJMoa1704795. Fink KR, Fink JR. Imaging of brain metastases. Surg Neurol Int. 2013, 4(Suppl 4):S209-19. doi: 10.4103/2152-7806.111298. Nayak L, Abrey L, Iwamoto F. Intracranial dural metastases. Cancer. 2009, 115:1947-53. doi: 10.1002/cncr.24203. Singh S, Agris J, Leeds N, Ginsberg L. Intracranial leptomeningeal metastases: comparison of depiction at FLAIR and contrast-enhanced MR imaging. Radiology. 2000, 217:50-3. doi: 10.1148/radiology.217.1.r00oc3550. Hayashida Y, Hirai T,...
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