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Congress: ECR25
Poster Number: C-27030
Type: Poster: EPOS Radiologist (scientific)
Authorblock: Y. Yang, H. Huang, Z. Wen; Beijing/CN
Disclosures:
Yuming Yang: Nothing to disclose
Hao Huang: Nothing to disclose
Zhiyong Wen: Nothing to disclose
Keywords: Genital / Reproductive system male, Oncology, Pelvis, MR, Computer Applications-Detection, diagnosis, Diagnostic procedure, Cancer, Neoplasia
Purpose The Prostate Imaging-Reporting and Data System (PI-RADS) version 2.1 has been recognized as the standard for prostate magnetic resonance imaging (MRI) reporting in prostate cancer detection and risk stratification. The weight of dynamic contrast-enhanced imaging is limited in this version since its evidence supporting of necessity is controversial [1-3]. For men with clinical suspicion of prostate cancer, undergoing prostate MRI without intravenous contrast agents, termed biparametric MRI (bpMRI), can reduce the MRI scanning time, lower the cost of examination for patients, and avoid the risks...
Read more Methods and materials We retrospectively analyzed 193 patients with pathologically confirmed prostate disease who underwent MRI examinations at Beijing Electric Power Hospital, Capital Medical University, from January 2014 to December 2023. Images was acquired using a 3.0T MRI scanner, and both multiparametric MRI (mpMRI) and bpMRI results were interpreted based on PI-RADS version 2.1. CsPCa was defined as any core with Gleason grade group ≥ 2 from transperineal biopsies based on the International Society of Urological Pathology Consensus [11, 12].In total, the following...
Read more Results Of the 193 patients included in total , CsPCa was detected in 64 patients (33.4%), and the other 129 patients were diagnosed with non-significant cancers or no malignant lesions. Logistic regression analysis demonstrated that f/tPSA, PSAD, bpMRI scores and mpMRI scores were independent predictors for CsPCa (P < 0.05).The bpMRI nomogram was established using f/tPSA, PSAD and bpMRI scores. [fig 1] The ROC curve analysis indicated that the bpMRI nomogram model showed a favorable diagnostic performance (AUC = 0.946, 95% CI: 0.904-0.973), which...
Read more Conclusion Our results indicate that bpMRI scores, f/tPSA and PSAD emerge as independent risk factors exerting influence on the risk of CsPCa. The bpMRI-based predictive model was internally validated and presented in the form of a nomogram. This nomogram has the potential to be used as an alternative tool for biopsy-naive patients who have difficulty undergoing mpMRI examinations, showing a satisfactory predictive value for CsPCa detection. It can provide substantial clinical reference value and help reduce the risk of unnecessary biopsies.
Read more References Schoots IG, Barentsz JO, Bittencourt LK, et al. PI-RADS Committee Position on MRI Without Contrast Medium in Biopsy-Naive Men With Suspected Prostate Cancer: Narrative Review. AJR Am J Roentgenol. 2021;216(1):3-19. doi:10.2214/AJR.20.24268 Schieda N, Krishna S, Davenport MS. Update on Gadolinium-Based Contrast Agent-Enhanced Imaging in the Genitourinary System. AJR Am J Roentgenol. 2019;212(6):1223-1233. Turkbey B, Rosenkrantz AB, Haider MA, et al. Prostate Imaging Reporting and Data System Version 2.1: 2019 Update of Prostate Imaging Reporting and Data System Version 2. Eur Urol. 2019;76(3):340-351. Porter...
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