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Congress: ECR24
Poster Number: C-22236
Type: EPOS Radiologist (educational)
DOI: 10.26044/ecr2024/C-22236
Authorblock: A. A. Basheer Ahmed1, K. Saravanan1, P. G. Elangovan1, V. Adhithiya1, F. Abubacker Sulaiman2; 1Melmaruvathur, Tamil Nadu/IN, 2Chennai/IN
Disclosures:
Ashraf Ahmed Basheer Ahmed: Nothing to disclose
K Saravanan: Nothing to disclose
Prem Gowtham Elangovan: Nothing to disclose
Vigneshwar Adhithiya: Nothing to disclose
Farook Abubacker Sulaiman: Nothing to disclose
Keywords: Contrast agents, Catheter arteriography, CT-Angiography, PET, Barium enema, Outcomes
Learning objectives Familiarize attendees with the latest developments in contrast agents for radiological imaging. Illustrate the improved diagnostic yield resulting from advanced contrast media. Forecast the potential impact of these innovations on clinical practice and patient outcomes.
Read more Background Contrast media used with imaging techniques to enhance the differences seen between the body tissues on the images. Contrast media alter the response of the tissues to the applied electromagnetic or ultrasound energy by a variety of mechanisms. The ideal contrast medium would achieve a very high concentration in the tissues without producing any adverse effects. Unfortunately, so far this has not been possible, and all contrast media have adverse effects. Radiographic Contrast Media: Positive and negative contrast agents. The positive contrast media attenuate...
Read more Findings and procedure details Nanoparticles (NPs) As a platform, nanoparticulates are compatible for developing targeted contrast agents, because: a)They have a surface, which can be functionalized with one or more targeting molecules at a wide range of densities.b)Their plasma circulation time can be turned over several orders of magnitude based on their physicochemical properties. Advances in nanotechnology may lead to a NP-based tumor-targeting contrast agent that will provide enhanced sensitivity and specificity for tumor imaging enabling earlier detection of metastases Biological interactions and clearance routes: The main parameters governing...
Read more Conclusion In the past several years, we have witnessed the emergence of more NIR-II organic contrast agents. Organic NIR-II dyes have been used for the detection of various biological and pathological processes and the diagnosis of diseases with deeper penetration depth and higher resolution. Despite the rapid development of the NIR-II dyes, there still exists room for improvements. Most of the NIR-II dyes were used for imaging near 1000 nm, and new imaging contrast agents for the NIR-II subwindows such as NIR-IIa and NIR-IIb windows...
Read more References 1.Contrast Media: Safety Issues and ESUR Guidelines | SpringerLink2.Neda Naseri, Elham Ajorlou, Fatemeh Asghari & Younes Pilehvar-Soltanahmadi (2018) An update on nanoparticle-based contrast agents in medical imaging, Artificial Cells, Nanomedicine, and Biotechnology, 46:6, 1111-1121, DOI: 10.1080/21691401.2017.13790143.Jiang, Zhen, et al. “Design and Application of Organic Contrast Agents for Molecular Imaging in the Second near Infrared (NIR-II) Window.” Photoacoustics, vol. 28, 1 Dec. 2022, pp. 100426–100426, https://doi.org/10.1016/j.pacs.2022.100426. Accessed 21 Dec. 2023.
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