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Congress: ECR25
Poster Number: C-23061
Type: Poster: EPOS Radiologist (educational)
DOI: 10.26044/ecr2025/C-23061
Authorblock: A. Farrugia1, S. Parayil Suresh2, S. M. Samed3; 1Basildon, Essex/UK, 2Essex/UK, 3Dubai/AE
Disclosures:
Alexia Farrugia: Nothing to disclose
Saneesh Parayil Suresh: Nothing to disclose
Sithara Muthaniyil Samed: Nothing to disclose
Keywords: Ear / Nose / Throat, Head and neck, Respiratory system, CT, CT-Angiography, MR, Education, eLearning, Infection, Inflammation, Tropical diseases
Learning objectives Learning objectives:1. To recognise the key radiologic findings associated with rhinocerebral and multisystemic mucormycosis across various imaging modalities, including CT and MRI2. To understand the pathophysiology of mucormycosis, its routes of spread, and how it manifests in different organ systems through radiologic evaluation.3. To recognise the role of cross-sectional imaging in guiding timely diagnosis, risk stratification, and therapeutic planning for patients with aggressive fungal infections like mucormycosis.
Read more Background Mucormycosis infection is a rare but life-threatening opportunistic fungal infection caused by fungi of the order Mucorales. It predominantly affects immunocompromised individuals, including those with diabetes mellitus, haematological malignancies, or those having organ transplants or on long-term corticosteroid therapy.Rhinocerebral mucormycosis is one of the most common forms, beginning in the nasal sinuses and spreading to the orbits, brain, and beyond through angioinvasion. The disease can progress rapidly, leading to vascular thrombosis, tissue necrosis, and systemic dissemination, making early diagnosis and...
Read more Findings and procedure details Cross-sectional imaging plays a pivotal role in the diagnosis, staging, and follow-up of mucormycosis. CT and MRI are the primary modalities used to detect: Sinus and soft tissue involvement, often presenting as mucosal thickening or non-enhancing necrotic areas. Orbital extension, characterized by proptosis, muscle involvement, and/or orbital apex syndrome. Intracranial spread, identified by cavernous sinus thrombosis, cerebral infarcts, or abscess formation. Multisystemic involvement may manifest as pulmonary involvement, spread to the gastrointestinal tract, or renal involvement, further complicating management. CT findings:Sinus Involvement: Non-enhancing soft tissue...
Read more Conclusion Mucormycosis is an aggressive fungal infection with high morbidity and mortality, especially in immunocompromised patients. Early detection and diagnosis are crucial for improving outcomes, as delays in intervention often lead to rapid disease progression and poor prognosis.The radiologic correlation with clinical findings is essential for prompt surgical debridement and initiation of antifungal therapy, which are the mainstays of treatment.
Read more References 1. Horger M, Hebart H, Schimmel H, Vogel M, Brodoefel H, Oechsle K, Hahn U, Mittelbronn M, Bethge W, Claussen CD. Disseminated mucormycosis in haematological patients: CT and MRI findings with pathological correlation. Br J Radiol. 2006 Sep;79(945):e88-95. doi: 10.1259/bjr/16038097. PMID: 16940368.2. Mazzai L, Anglani M, Giraudo C, Martucci M, Cester G, Causin F. Imaging features of rhinocerebral mucormycosis: from onset to vascular complications. Acta Radiol. 2022 Feb;63(2):232-244. doi: 10.1177/0284185120988828. Epub 2021 Feb 20. PMID: 33615823.3. Pai V, Sansi R,...
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