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Congress: ECR25
Poster Number: C-27692
Type: Poster: EPOS Radiologist (educational)
DOI: 10.26044/ecr2025/C-27692
Authorblock: D. A. Andres, D. Haba, B. I. Dobrovat, E. A. Marciuc; Iasi/RO
Disclosures:
Diana Andres Andres: Nothing to disclose
Danisia Haba: Nothing to disclose
Bogdan Ionut Dobrovat: Nothing to disclose
Emilia Adriana Marciuc: Nothing to disclose
Keywords: Neuroradiology brain, Oncology, MR, MR-Diffusion/Perfusion, MR-Spectroscopy, Biopsy, Contrast agent-intravenous, Metastases, Multidisciplinary cancer care, Neoplasia
Learning objectives Distinguishing between high grade glioma and solitary metastasis is crucial for the subsequent planning of further workup and treatment.The aim of this study is to ascertain whether various morphological parameters using conventional MRI, perfusion-weighted and proton spectroscopic MR imaging can be utilised to differentiate high-grade primary gliomas and solitary metastases on the basis of differences in vascularity and metabolite levels in the peritumoral region.
Read more Background Thirty-six patients with a solitary brain tumor (20 gliomas, 16 metastases) underwent conventional, contrast material–enhanced perfusion-weighted, and proton spectroscopic magnetic resonance imaging before surgical resection or stereotactic biopsy at our neurology and neurosurgery specialized center from April 2024 to December 2024. All patients had a previously untreated solitary enhancing brain tumor and peritumoral non-enhancing lesion and had undergone conventional brain MRI and DWI before surgical intervention. Patients with infratentorial lesion were excluded, as were those with a previous history of...
Read more Findings and procedure details The peritumoral region was defined as the area in the white matter immediately adjacent to the enhancing (hyperintense on T2-weighted images, but not enhancing on postcontrast T1-weighted images) portion of the tumo.To ascertain whether there were differences in the morphologic parameters of enhancing tumors, we analysed their shape, margins, and enhancement patterns on postcontrast T1-weighted images.  Furthermore, the aim was to detect peritumoral neoplastic cell infiltration by visual assessment of T2-weighted and diffusion-weighted images, including DWI, ADC maps. Relative cerebral...
Read more Conclusion In the process of distinguishing high grade glioma from solitary metastatic lesions, the application of visual morphologic assessment to tumoral and peritumoral regions, employing conventional MRI and diffusion-based techniques, can occasionally yield a more comprehensive diagnostic picture. While conventional MRI characteristics of solitary metastases and primary high-grade gliomas may exhibit similarity, advances in imaging technology, such as perfusion-weighted and spectroscopic MR imaging, have facilitated the distinction between these two distinct entities.
Read more References Brandao, L.A. and Domingues, R.C. (2004) ‘Intracranial neoplasms’, in MR spectroscopy of the brain. Philadelphia, USA: LWW, pp. 10. Hollingworth, W., Medina, L.S., Lenkinski, R.E., Shibata, D.K., Bernal, B., Zurakowski, D., et al. (2006) ‘A systematic literature review of magnetic resonance spectroscopy for the characterization of brain tumors’, AJNR. Möller-Hartmann, W., Herminghaus, S., Krings, T., Marquardt, G., Lanfermann, H., Pilatus, U., et al. (2022) ‘Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions’, Neuroradiology. Cai, J.-Z., Cao, D.,...
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