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Congress: ECR25
Poster Number: C-27535
Type: Poster: EPOS Radiologist (scientific)
DOI: 10.26044/ecr2025/C-27535
Authorblock: A. B. Kale, B. Dogan, M. Faraşat, G. Pekindil; Manisa/TR
Disclosures:
Ahmet Burak Kale: Nothing to disclose
Betul Dogan: Nothing to disclose
Mustafa Faraşat: Nothing to disclose
Gökhan Pekindil: Nothing to disclose
Keywords: Abdomen, Liver, Elastography, Ultrasound, Diagnostic procedure, Metabolic disorders
Purpose To investigate the usability of noninvasive sonoelastographic methods, including point-SWE and the newly developed auto-pSWE and UDFF values obtained using the DAX probe, in differentiating cases of hepatosteatosis and steatohepatitis, and to determine cutoff values for fibrosis detection.
Read more Methods and materials Patients referred for liver biopsy were prospectively evaluated using the Siemens ACUSON Sequoia device. Point-SWE values were obtained using an abdominal probe with ten separate measurements at a single point. Auto-pSWE and UDFF values were measured using a DAX probe with a 3×4 cm region of interest (ROI), which simultaneously acquired measurements from 15 different points, with three different measurements performed.
Read more Results In this study, a total of 50 patients were included and subjected to histopathological evaluation. Based on the findings, 10 patients were diagnosed with simple hepatosteatosis, whereas 26 patients were found to have steatohepatitis. Additionally, 10 patients who exhibited normal histological characteristics were assigned to the control group. Among the individuals diagnosed with steatohepatitis, fibrosis was detected in 13 cases, while the remaining 13 patients showed no histopathological evidence of fibrosis.The assessment of shear wave elastography parameters revealed that median...
Read more Conclusion UDFF and auto-pSWE measured using the DAX probe represent promising ultrasound-based, quantitative, and noninvasive biomarkers for detecting hepatosteatosis and fibrosis, as well as for predicting steatohepatitis in clinical practice.These results highlight the complex interplay between liver stiffness, fat content, and histopathological activity, underscoring the need for comprehensive diagnostic approaches in MASLD and steatohepatitis evaluation.
Read more References Harrison, S. A., Torgerson, S., & Hayashi, P. H. (2003). The natural history of nonalcoholic fatty liver disease: a clinical histopathological study. The American journal of gastroenterology, 98(9), 2042–2047. Torres, D. M., & Harrison, S. A. (2008). Diagnosis and therapy of nonalcoholic steatohepatitis. Gastroenterology, 134(6), 1682–1698.
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