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Congress: ECR25
Poster Number: C-16479
Type: Poster: EPOS Radiologist (scientific)
Authorblock: E. Tebaldi, M. Grisoli, F. M. Doniselli; Milan/IT
Disclosures:
Elisa Tebaldi: Nothing to disclose
Marina Grisoli: Nothing to disclose
Fabio Martino Doniselli: Nothing to disclose
Keywords: Neuroradiology brain, Radiographers, MR, Diagnostic procedure, Education, Imaging sequences, Seizure disorders
Purpose This study reviews the literature to investigate and compare the characteristics of inversion recovery (IR) sequences in MRI protocols for epilepsy. The aim is to summarize how different IR sequences, such as Fluid-Attenuated Inversion Recovery (FLAIR), Double Inversion Recovery (DIR) and others, contribute to the detection of epileptogenic lesions and assess their effectiveness in clinical applications.
Read more Methods and materials A systematic literature review was conducted in March 2024 using databases such as PubMed, EMBASE, and Google. The search focused on the association between epilepsy and IR sequences in MRI, while subsequent searches explored the relationship between epilepsy and specific IR sequences. Additionally, further relevant articles were identified through reference analysis and a review of supplementary bibliographies.Exclusion criteria included non-English publications, studies exclusively addressing temporal lobe epilepsy and papers published before 1995.A total of 384 papers were initially identified, with...
Read more Results The review highlighted that all IR sequences have their own characteristics, making some more suitable than others depending on the specific requirements of the study.FLAIR sequences, especially 3D FLAIR with isotropic voxels and reduced slice thickness [1,2], are essential for detecting cortical and subcortical abnormalities [3], improving spatial resolution and minimising artifacts.DIR  images can generate signals from a specific tissue while nulling the signals from further tissues, therefore it offers enhanced sensitivity in identifying cortical dysplasias [4]. Also, it has...
Read more Conclusion IR sequences developed over the years have proved their crucial role in advancing methods for identifying epileptogenic areas, ultimately improving surgical outcomes and fostering the development of innovative techniques. However, scientific evidence comparing the effectiveness of different IR sequences remains fragmented, lacking a systematic evaluation of the available diagnostic tools.Moreover, research has demonstrated that high magnetic fields provide significant advantages over lower-field imaging in epilepsy studies, with ultra-high field MRI expected to play an increasingly pivotal role in the future....
Read more References 1 - Wieshmann UC, Barker GJ, Symms MR, Bartlett PA, Stevens JM, Shorvon SD.  Fast fluid-attenuated inversion-recovery imaging: first experience with a 3D version in epilepsy.  Neuroradiology. 1998 Aug;40(8):483-9.  doi: 10.1007/s002340050630. PMID: 9763334.  2 - Henriette J. Tschampa, Horst Urbach, Michael Malter, Rainer Surges, Susanne Greschus, Jürgen Gieseke, Magnetic resonance imaging of focal cortical dysplasia: Comparison of 3D and 2D fluid attenuated inversion recovery sequences at 3T, Epilepsy Research, Volume 116, 2015, Pages 8-14, ISSN 0920-1211, https://doi.org/10.1016/j.eplepsyres.2015.07.004. 3 - Boutet A, Loh A, Chow CT, Taha A, Elias GJB, Neudorfer C,...
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