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Congress: ECR25
Poster Number: C-25635
Type: Poster: EPOS Radiologist (educational)
Authorblock: R. Pavlyuk, O. Sas; Kyiv/UA
Disclosures:
Romanna Pavlyuk: Nothing to disclose
Olena Sas: Nothing to disclose
Keywords: Bones, Hybrid Imaging, Oncology, CT, MR-Diffusion/Perfusion, PET-CT, Diagnostic procedure, Technology assessment, Cancer, Image verification, Outcomes
Learning objectives As of 2024, the ability to use diagnostic PET-CT in Ukraine is extremely low due to an acute shortage of both specialized equipment and radiopharmaceuticals. These limitations are further exacerbated by the difficult economic situation, which has been seriously affected by the war with Russia. Despite these limitations, many cancer centers are trying to provide comprehensive cancer imaging services. Against this backdrop, whole-body diffusion-weighted magnetic resonance imaging (DWI) is gaining attention as an alternative method for detecting metastatic lesions in...
Read more Background Study design and patient cohortOver the course of three months, 13 patients (4 men and 9 women, aged 46-73 years) with various oncological diagnoses participated in the study. Among them were patients with breast cancer, prostate cancer, synonasal carcinoma, lymphoma, and other solid tumors. Each of them had either confirmed advanced disease or strong clinical indicators (e.g., elevated tumor markers, persistent pain) that indicated suspected metastatic spread. Although CT is the main method for primary cancer diagnosis in Ukraine, the...
Read more Findings and procedure details Detection of metastases in 13 patients In this study, all 13 patients underwent both CT and WB-DWI, which allowed for a direct comparison. In most of them, malignant lesions were detected in various localizations, including bones, visceral organs, lymph nodes, and soft tissues. Bone metastases. In each case where CT scan indicated a high suspicion of bone involvement, WB-DWI confirmed the metastatic nature of the lesion by demonstrating restricted diffusion. In 2 of these 13 patients with breast cancer and synonasal carcinoma,...
Read more Conclusion In situations with limited access to PET-CT, WB-DWI can be a powerful method for detecting metastases.Due to its high sensitivity, the ability to visualize the entire body, and the absence of radiation exposure, this method can be used as an alternative or complement to CT in oncological diagnosis, especially for long-term patient monitoring. At the same time, the method requires further research to optimize protocols, increase specificity, and expand its application in various cancer scenarios.
Read more References Heindel, W., Gübitz, R., Vieth, V., Weckesser, M., Schober, O., & Schäfers, M. (2014). The diagnostic imaging of bone metastases. Deutsches Ärzteblatt International, 111(44), 741. Lecouvet, F. E., Larbi, A., Pasoglou, V., Omoumi, P., Tombal, B., Michoux, N., ... & Vande Berg, B. C. (2013). MRI for response assessment in metastatic bone disease. European radiology, 23, 1986-1997. Schraml, C., Schwenzer, N. F., Sperling, O., Aschoff, P., Lichy, M. P., Müller, M., ... & Pfannenberg, C. (2013). Staging of neuroendocrine tumours: comparison of...
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