Reported p values refer to the differences between series I and III, as well as between series I and IV. The mean ratings across series I-IV were as follows: 3.1/3.7/4.3/4.8 for category A (both p<0.001); 3.2/4.1/4.1/3.5 for category B (p<0.001, p=0.002); 3.0/3.8/4.5/4.8 for category C1 (both p<0.001); 3.0/4.2/4.2/3.4 for category C2 (both p<0.001); 4.3/4.3/4.4/4.4 for category D1 (p=0.02, p=0.03); 4.2/4.4/4.3/4.2 for category D2 (p=0.25, p=0.79); 3.1/3.8/4.4/4.8 for category E1 (both p<0.001); and 3.1/4.1/3.9/3.4 for category E2 (both p<0.001). Furthermore, the mean overall diagnostic confidence ranking was 3.9/2.9/2.1/1.1 for lung (both p<0.001) and 3.5/1.9/1.9/2.7 for tissue (both p<0.001) across series I-IV, respectively. Figure 2 shows a magnification of a direct comparison between series II (DLR) and IV (SR-DLR). Figure 3 summarizes the results.