This exhibit includes patients with Behçet’s disease who were evaluated using various imaging modalities at our institute to demonstrate different radiologic findings, alongside a review of the current literature.

Behçet's disease is a systemic auto-inflammatory vasculitis of unknown etiology, with its pathogenesis likely involving environmental factors acting on a genetic predisposition, linked to various epigenetic modifications (such as HLA-B51 mutations). The disease typically affects young adults and impacts both genders equally, though it tends to follow a more severe course in males and younger individuals. Behçet's disease has traditionally been referred to as "Silk Road Disease" due to its geographic distribution, where the highest incidence is found along regions historically associated with the Silk Road. A clinical triad of oral ulcers, genital ulcers, and uveitis is characteristic of the disease, with additional manifestations later described, including involvement of the skin, joints, large vessels, lungs, brain, and gastrointestinal and genitourinary tracts.