We retrospectively identified patients with an incident diagnosis of ACS or CCS in the U.S. administrative claims data Optum’s de-identified Clinformatics® Data Mart (CDM), between 1/1/2016 and 30/6/2021. CDM is derived from a database of administrative health claims for members of large commercial and Medicare Advantage health plans. CDM is statistically de-identified under the Expert Determination method consistent with HIPAA and managed according to Optum® customer data use agreements. The population is geographically diverse, spanning all 50 states.

The first recorded diagnosis was considered as the index date, using ICD-10 codes to identify patients. The measures were created using the following ICD-10 codes. ACS: I20.* Angina pectoris, I21.* Acute myocardial infarction, I22.* Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction, I23.* Certain current complications following ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction (within the 28 day period), I24.* Other acute ischemic heart diseases; CCS: I25.* Chronic ischemic heart disease. For each ICD-10 code category, all billable codes were included, e.g. for I20.* for I20.0 Unstable angina, I20.1 Angina pectoris with documented spasm, etc.

A baseline period of six months before the index date was applied to exclude patients with a previous history of ACS or CCS. The diagnostic techniques that patients underwent in the baseline period and up to 12 months following their diagnosis were analyzed.

The first recorded diagnosis was considered as the index date, using ICD-10 codes to identify patients. The measures were created using the following ICD-10 codes. ACS: I20.* Angina pectoris, I21.* Acute myocardial infarction, I22.* Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction, I23.* Certain current complications following ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction (within the 28 day period), I24.* Other acute ischemic heart diseases; CCS: I25.* Chronic ischemic heart disease. For each ICD-10 code category, all billable codes were included, e.g. for I20.* for I20.0 Unstable angina, I20.1 Angina pectoris with documented spasm, etc.

A baseline period of six months before the index date was applied to exclude patients with a previous history of ACS or CCS. The diagnostic techniques that patients underwent in the baseline period and up to 12 months following their diagnosis were analyzed.

The first recorded diagnosis was considered as the index date, using ICD-10 codes to identify patients. The measures were created using the following ICD-10 codes. All billable codes were included in the measures. ACS: I20.* Angina pectoris, I21.* Acute myocardial infarction, I22.* Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction, I23.* Certain current complications following ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction (within the 28 day period), I24.* Other acute ischemic heart diseases; CCS: I25.* Chronic ischemic heart disease. For each ICD-10 code category, all billable codes were included, e.g. for I20.* for I20.0 Unstable angina, I20.1 Angina pectoris with documented spasm, etc.

A baseline period of six months before the index date was applied to exclude patients with a previous history of ACS or CCS. The diagnostic techniques that patients underwent in the baseline period and up to 12 months following their diagnosis were analyzed.