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Congress: ECR25
Poster Number: C-27458
Type: Poster: EPOS Radiologist (scientific)
Authorblock: V. Corato, R. Valletta, B. Proner, V. Vingiani, M. Bonatti; Bolzano/IT
Disclosures:
Valentina Corato: Nothing to disclose
Riccardo Valletta: Nothing to disclose
Bernardo Proner: Nothing to disclose
Vincenzo Vingiani: Nothing to disclose
Matteo Bonatti: Nothing to disclose
Keywords: Genital / Reproductive system male, MR, Imaging sequences, Neoplasia
Results

The final study population consisted of 45 patients with a median age of 71 years (IQR 66–76). Early contrast enhancement on DCE was present in 26 of the 45 lesions (57.8%) and absent in 19/45 (42.2%) of them. On ASL, the median prostate blood flow (PBF) was 27.00 ml/100g/min (IQR 19.25–44.31) within the lesions, compared to 15.76 ml/100g/min (IQR 11.25–20.47) in the normal peripheral zone, resulting in a median lesion-to-prostate PBF ratio of 1.84 (IQR 1.19–2.89).

Fig 3: Median PBF of the lesions (right) was significantly higher than median PBF of normal prostate (left).
Lesion-to-prostate PBF ratio was significantly higher in DCE-positive lesions compared to DCE-negative ones, with median values of 2.78 (IQR 2.25–3.16) versus 1.12 (IQR 0.91–1.26) (p < 0.0001).
Fig 4: Lesion-to-ptostate PBF ratio was significantly higher in DCE+ lesions than in DCE- ones.
ROC analysis demonstrated that the PBF ratio was highly effective in distinguishing between DCE-positive and DCE-negative lesions, with an AUC of 0.986 (95% CI 0.891–1.000).
Fig 5: Lesion-to-ptostate PBF ratio showed an AUC=0.986 for discriminating DCE+ lesions from DCE- ones.
A cut-off value of 1.66 provided a sensitivity of 91.7% and a specificity of 100% for identifying DCE-positive lesions.
GALLERY