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Congress: ECR25
Poster Number: C-23126
Type: Poster: EPOS Radiologist (scientific)
DOI: 10.26044/ecr2025/C-23126
Authorblock: E. Pershina, K. Kovalev, Z. Magomedova, D. Shchekochikhin; Moscow/RU
Disclosures:
Ekaterina Pershina: Nothing to disclose
Konstantin Kovalev: Nothing to disclose
Zaynab Magomedova: Nothing to disclose
Dmitry Shchekochikhin: Nothing to disclose
Keywords: Cardiac, MR, Contrast agent-intravenous, Hyperplasia / Hypertrophy, Tissue characterisation
Results

In this study, healthy controls, with an average age of 47.5±15.2 years, were younger than both the HCM patients, who averaged 53.9±10.5 years, and the LVH patients, who averaged 58.5±14.5 years (p=0.01). There were no significant differences in sex distribution between the groups. Several strain parameters exhibited significant differences between the HCM and LVH groups, pointing to distinct myocardial deformation patterns

Table 1: Strain parameter differences between HCM, LVH, and healthy control groups
. Specifically, myocardial strain analysis revealed that HCM patients exhibited significantly reduced radial contractility. This was evidenced by lower 2D long-axis values (19.2±8.1% vs. 23.6±6.9%, p=0.01) and 3D radial strain values (41±22% vs. 45.2±16.8%, p=0.04) compared to patients with LVH. Furthermore, longitudinal function was markedly impaired in HCM patients, with significantly diminished 2D long-axis (-11.3±3.7% vs. -13.2±3.2%, p=0.02) and 3D longitudinal strain (-7.8±4.5% vs. -9.9±5.0%, p=0.003). These findings were further underscored by the observation of even higher longitudinal strain values in healthy controls, highlighting the unique myocardial characteristics that differentiate HCM from LVH.

GALLERY