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Congress: ECR25
Poster Number: C-10868
Type: Poster: EPOS Radiologist (scientific)
Authorblock: P. G. Lacaita, F. Plank, C. Beyer, M. Stühlinger, G. Widmann, G. M. Feuchtner; Innsbruck/AT
Disclosures:
Pietro Giacomo Lacaita: Nothing to disclose
Fabian Plank: Nothing to disclose
Christoph Beyer: Nothing to disclose
Markus Stühlinger: Nothing to disclose
Gerlig Widmann: Nothing to disclose
Gudrun Maria Feuchtner: Nothing to disclose
Keywords: Cardiac, Cardiovascular system, CT, CT-Angiography, Computer Applications-Detection, diagnosis, Image registration, Tissue characterisation
Results
      • Of 137 patients screened (mean age 59.8 years, 27.7% female), 108 were included.
        Table 1: Study cohort
      • Late enhancement (LE) was more prevalent in patients with LAWT > 2mm compared to LAWT 1.5mm (91.7% vs. 80.2%, p=0.022).
      • Of  78 patients with LE, 60 (77.1%) had focal, 13 (16.5%) diffuse, and 5 (6.3%) mixed patterns. 
      • There was a weak correlation between increasing LAWT and the density of LE (HU)(r=0.229; p=0.041).
        Fig 4: Correlation of LAWT vs LE (HU)
      • For detection of LE, interobserver agreement was good with kappa 0.895 (95% CI: 0.82-964, p<0.001).
      • Agreement of LE-CT with electroanatomical mapping (EAM), low voltage areas (LVA) <0.5mV was 80%, in a subset of 30 patients.
        Fig 5: 59 years-old-male with paroxymal AF. left atrial wall thickness (LAWT) 3.3mm, with a low voltage area on EAM (anterior LA wall (green/yellow area) (upper panel) matching with focal LE (128 HU) on late enhancement (LE) CT (lower panels).
      • Artifacts: LA wall artifacts had a higher CT density than LE (p=0.002).
      • The effective radiation dose for LE-CT was low with 0.95mSv (range 0.52-1.2mSv).
      • Inter- and Intraobserver Agreement (Bland Altman Plots) for LAWT was high
        Fig 6: Intraobserver agreement (Bland altman plot) was excellent (mean error +0.003)
        Fig 7: Interobserver agreement (Bland altman plot) was excellent (mean error +0.07)

    Study limitation:  Explorative pilot study, small sample size, retrospective design

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