Congress:
ECR25
Poster Number:
C-10868
Type:
Poster: EPOS Radiologist (scientific)
Authorblock:
P. G. Lacaita, F. Plank, C. Beyer, M. Stühlinger, G. Widmann, G. M. Feuchtner; Innsbruck/AT
Disclosures:
Pietro Giacomo Lacaita:
Nothing to disclose
Fabian Plank:
Nothing to disclose
Christoph Beyer:
Nothing to disclose
Markus Stühlinger:
Nothing to disclose
Gerlig Widmann:
Nothing to disclose
Gudrun Maria Feuchtner:
Nothing to disclose
Keywords:
Cardiac, Cardiovascular system, CT, CT-Angiography, Computer Applications-Detection, diagnosis, Image registration, Tissue characterisation
- Of 137 patients screened (mean age 59.8 years, 27.7% female), 108 were included. Table 1: Study cohort
- Late enhancement (LE) was more prevalent in patients with LAWT > 2mm compared to LAWT 1.5mm (91.7% vs. 80.2%, p=0.022).
- Of 78 patients with LE, 60 (77.1%) had focal, 13 (16.5%) diffuse, and 5 (6.3%) mixed patterns.
- There was a weak correlation between increasing LAWT and the density of LE (HU)(r=0.229; p=0.041).Fig 4: Correlation of LAWT vs LE (HU)
- For detection of LE, interobserver agreement was good with kappa 0.895 (95% CI: 0.82-964, p<0.001).
- Agreement of LE-CT with electroanatomical mapping (EAM), low voltage areas (LVA) <0.5mV was 80%, in a subset of 30 patients. Fig 5: 59 years-old-male with paroxymal AF. left atrial wall thickness (LAWT) 3.3mm, with a low voltage area on EAM (anterior LA wall (green/yellow area) (upper panel) matching with focal LE (128 HU) on late enhancement (LE) CT (lower panels).
- Artifacts: LA wall artifacts had a higher CT density than LE (p=0.002).
- The effective radiation dose for LE-CT was low with 0.95mSv (range 0.52-1.2mSv).
- Inter- and Intraobserver Agreement (Bland Altman Plots) for LAWT was high Fig 6: Intraobserver agreement (Bland altman plot) was excellent (mean error +0.003)Fig 7: Interobserver agreement (Bland altman plot) was excellent (mean error +0.07)
Study limitation: Explorative pilot study, small sample size, retrospective design