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Congress: ECR25
Poster Number: C-14271
Type: Poster: EPOS Radiologist (scientific)
Authorblock: M. R. López De La Torre Carretero, M. B. Barrio Piqueras, C. D. Solano, D. A. Zambrano, A. M. Delgado Brito, J. M. Rodríguez Ortega, C. Mbongo, A. Elizalde, L. J. Pina Insausti; Pamplona/ES
Disclosures:
Manuel Rafael López De La Torre Carretero: Nothing to disclose
Miguel Barrio Barrio Piqueras: Nothing to disclose
Carlos Delgado Solano: Nothing to disclose
Daniel Alfonso Zambrano: Nothing to disclose
Adolfo Manuel Delgado Brito: Nothing to disclose
José Marlon Rodríguez Ortega: Nothing to disclose
Carmen Mbongo: Nothing to disclose
Arlette Elizalde: Nothing to disclose
Luis Javier Pina Insausti: Nothing to disclose
Keywords: Breast, Oncology, Mammography, MR, Comparative studies, Screening, Staging, Cancer, Neoplasia, Outcomes
Purpose Breast cancer is the most prevalent malignancy among women worldwide, with a total of 6,677 deaths attributed to this disease in 2022, and 36,395 new cases estimated for 2024. Once diagnosed, the most accurate extension study during preoperative staging is vital to decide the most optimal strategy, being also crucial to detect additional ipsilateral or contralateral lesions. Breast MRI is a widely used method for preoperative staging of breast cancer [1, 2]. [fig 1] MRI is a morphofunctional technique based on tumoral...
Read more Methods and materials Patient selectionBetween September 2017 and November 2023, we conducted a retrospective and multitechnique approach, focused on confirmed breast cancer cases in patients who underwent both MRI and CEM. A comprehensive dataset was compiled, including patient age, breast density pattern, CEM and MRI results, histological characterization and size of each lesion, and any additional lesions discovered during the examinations. Image evaluationTwo radiologists retrospectively reevaluated all images in both techniques.Breast density was assessed using ACR criteria and background parenchymal enhancement (BPE) was...
Read more Results Demographics: A total of 139 histopathologically confirmed lesions from 94 women were included. The mean age of the patients was 58, with 34 women in the young subgroup (<50 years old) and 61 in the old subgroup (≥50). The distribution of ACR classification groups was 18 patients conforming to non-dense breasts (A and B) and 76 patients in dense breasts (C and D) subgroups. [fig 9] Background Parenchymal Enhancement (BPE): MRI demonstrated a higher degree of BPE compared to CEM, with median...
Read more Conclusion Breast MRI yielded significantly higher sensitivity. The AUC of CEM exceeded that of MRI due to the higher rate of FP obtained in MRI examinations.In the preoperative assessment of malignant breast lesions, a higher rate of FP (as seen in MRI) is more acceptable than a high rate of FN (as seen in CEM), considering the risk of failing to diagnose intermediate-risk tumors with this technique.Regarding tumor size measurements, both CEM and MRI demonstrated comparable performance, with a tendency to...
Read more References References REDECAN RE de R de C (2024) Las cifras del cáncer en España. In: Soc. española Oncol. médica. https://seom.org/images/publicaciones/informes-seom-de-evaluacion-de-farmacos/LAS_CIFRAS_2024.pdf. Accessed 24 Jun 2024 Muradali D, Fletcher GG, Cordeiro E, et al (2023) Preoperative Breast Magnetic Resonance Imaging: An Ontario Health (Cancer Care Ontario) Clinical Practice Guideline. Curr Oncol 30:6255–6270. https://doi.org/10.3390/curroncol30070463 Knopp MV, Weiss E, Sinn HP, et al (1999) Pathophysiologic basis of contrast enhancement in breast tumors. J Magn Reson Imaging 10:260–266. https://doi.org/10.1002/(SICI)1522-2586(199909)10:3<260::AID-JMRI6>3.0.CO;2-7 Carmeliet P, Jain RK (2000) Angiogenesis in cancer and other...
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