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Congress: ECR25
Poster Number: C-12594
Type: Poster: EPOS Radiologist (scientific)
DOI: 10.26044/ecr2025/C-12594
Authorblock: M. Sebastian1, S. Cicilet1, S. Basheer2; 1Bangalore/IN, 2Alappuzhq/IN
Disclosures:
Midhila Sebastian: Nothing to disclose
Soumya Cicilet: Nothing to disclose
Shameer Basheer: Nothing to disclose
Keywords: CNS, MR, Imaging sequences, Ischaemia / Infarction
Purpose Estimate proportion of DWI detected HIE cases among provisionally diagnosed HIE in neonates. To determine whether 1 minute APGAR score is predictive of presence of MRI findings in HIE in neonates. Correlation between APGAR score and MRI findings. To study the spectrum of MRI findings in hypoxic ischemic encephalopathy in preterm and term infants in the age group of 0-28 days.
Read more Methods and materials Hypoxic ischemic encephalopathy consists of a spectrum of brain abnormalities happening in the scenario of perinatal asphyxiaHIE is one of the leading causes resulting in cerebral palsy and other severe neurological deficits in children.Conventional MRI identifies hypoxic brain injury after 24 hours, particularly after day 4. Novel MRI imaging modalities like diffusion-weighted imaging allow for faster diagnosis by relying on the restriction of diffusion in abnormal areas. DWI pseudo normalizes after about 7 days, during which conventional MRI is particularly...
Read more Results 71.43 % of infants in our study were born at term, and 28.57% were preterm. DWI Sensitivity: Detected diffusion restriction in 91.43% of cases. Superior to conventional T1/T2 MRI, which detected 62.86%. [fig 13] [fig 14] APGAR Score Correlation: Trend observed: Lower APGAR scores linked to more severe MRI abnormalities. Not statistically significant (P > 0.05). [fig 15] MRI Patterns: Differences noted between preterm and term infants DWI effectiveness limited in later stages of HIE. Of 35 neonates assessed, DWI proved more sensitive, detecting diffusion restriction in 91.43% of cases compared to 62.86% with conventional MRI....
Read more Conclusion This cross-sectional study evaluated the utility of diffusion-weighted imaging (DWI) compared to conventional T1/T2 MRI in detecting neonatal hypoxic-ischemic encephalopathy (HIE). DWI was found to be significantly more sensitive, identifying diffusion restriction in 91.43% of cases versus 62.86% with conventional MRI. Although a trend suggested lower 1-minute APGAR scores was associated with more severe MRI findings, this correlation was not statistically significant. The study also highlighted distinct MRI patterns in preterm and term infants, with DWI proving valuable in early...
Read more References 1.Chao CP, Zaleski CG, Patton AC. Neonatal hypoxic-ischemic encephalopathy: multimodality imaging findings. Radiographics. 2006;26 Suppl 1 : S159-72. doi:10.1148/rg.26si0655042.Heinz ER, Provenzale JM. Imaging findings in neonatal hypoxia: a practical review. AJR Am J Roentgenol. 2009;192 (1): 41-7. doi:10.2214/AJR.08.1321 3.Villani F, D'Incerti L, Granata T et-al. Epileptic and imaging findings in perinatal hypoxic-ischemic encephalopathy with ulegyria. Epilepsy Res. 2003;55 (3): 235-43. 4.Gökçe E & Çevik B. Evaluation of Different Ulegyria Patterns with Magnetic Resonance Imaging. J Clin Neurosci. 2018;58:148-55. doi:10.1016/j.jocn.2018.09.006  
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