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Congress: ECR25
Poster Number: C-23224
Type: Poster: EPOS Radiologist (educational)
DOI: 10.26044/ecr2025/C-23224
Authorblock: A. Ben Khalifa, I. Dkhil, M. Ben Hafsa, S. Jelassi, A. Jelassi, M. Inoubli, I. Bouzaouache, D. Nouri, S. Nagi; TUNIS/TN
Disclosures:
Asma Ben Khalifa: Nothing to disclose
Insaf Dkhil: Nothing to disclose
Meriem Ben Hafsa: Nothing to disclose
Soumaya Jelassi: Nothing to disclose
Achref Jelassi: Nothing to disclose
Marwa Inoubli: Nothing to disclose
Ines Bouzaouache: Nothing to disclose
Dorsaf Nouri: Nothing to disclose
Sonia Nagi: Nothing to disclose
Keywords: CNS, MR, Decision analysis, Education and training
Learning objectives To provide a radiological overview of the limbic system, focusing on: The anatomy of the limbic system and its association tracts. The functional correlations of limbic structures. Neuroimaging findings in key limbic system pathologies, with emphasis on MRI.
Read more Background The limbic system is a complex network integrating cortical, subcortical, and diencephalic structures critical for memory, learning, emotion, and behavior. It comprises key anatomical components (Figure 1-3): Cortical structures: Cingulate gyrus, para-hippocampal gyrus, and entorhinal cortex. Subcortical structures: Hippocampus, amygdala, septal nuclei. Diencephalic structures: Thalamus, hypothalamus, mammillary bodies. Association tracts: Fornix, cingulum bundle, stria terminalis, uncinate fasciculus. The limbic system is frequently involved in a spectrum of neurological disorders, including epilepsy, encephalitis, neurodegenerative diseases, and psychiatric conditions (1).Anatomy and Functional Overview of the Limbic SystemThe...
Read more Findings and procedure details To achieve optimal imaging of the limbic system, the following MRI sequences and parameters are recommended: High-resolution 3D T1-weighted imaging Purpose: To assess structural abnormalities such as atrophy or malformation (5). Parameters: Slice thickness 1-1.5 mm, no gap, field of view (FOV) 220–250 mm. T2-weighted imaging Purpose: To detect lesions, hyperintensities, and signs of inflammation (6). Parameters: Slice thickness 4-5 mm, FOV 220–250 mm, TE: 100-120 ms. FLAIR (Fluid Attenuated Inversion Recovery) Purpose: To identify hyperintensities associated with inflammatory or infectious conditions (6–8). Parameters: Slice thickness...
Read more Conclusion The limbic system’s intricate anatomical and functional architecture is well-explored through neuroimaging, particularly MRI and advanced techniques like DTI, fMRI, and spectroscopy. Radiological evaluation allows early detection of limbic pathology, guiding diagnosis and management in epilepsy, neurodegeneration, and psychiatric disorders. Understanding these imaging findings enhances our ability to correlate radiology with clinical outcomes, thus improving patient care.
Read more References Bartsch T. Selective neuronal vulnerability of human hippocampal CA1 neurons: lesion evolution, temporal course, and pattern of hippocampal damage in diffusion-weighted MR imaging. 2015; Duvernoy HM, Cattin F, Naidich TP, Raybaud C, Risold PY, Salvolini U. The Human Hippocampus: Functional Anatomy, Vascularization and Serial Sections with MRI, 3rd edition. Aggleton JP, éditeur. The Amygdala: A functional analysis [Internet]. Oxford University PressOxford; 2000 [cité 5 janv 2025]. Disponible sur: https://academic.oup.com/book/52889 The Human Central Nervous System, 4th ed. AJNR Am J Neuroradiol. mai 2008;29(5):e39‑e39. Abdelhalim AN,...
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