This study collected 3140 T2DM patients from September 2011 to February 2022. Finally, 2820 eligible T2DM patients (1768 males, age 68.35 ± 10.52) who underwent CCTA were used in the study. Risk stratification assessment for atherosclerotic cardiovascular disease and the determination of corresponding LDL-C management goals were conducted in accordance with the 2019 European Society of Cardiology/European Atherosclerosis Society Guidelines. The four branches of coronary artery tree were divided into 16 segments, and the degree and extent of stenosis caused by detected plaques in each segment were visually evaluated and graded. The plaque involvement degree (PID), segment involvement score (SIS) and segment stenosis score (SSS) were calculated to assess the burden of coronary plaques. The high-risk coronary plaques including low-attenuation plaque, positive remodeling, spotty calcification, napkin-ring sign. Comparative analysis of differences in coronary plaque characteristics was performed for the patients between the normal LDL-C level group and the abnormal LDL-C level group.