13 first order features and 15 second order feature variables demonstrated a statistically significant difference (p<0.0001). Some first order features which were significantly different between parathyroid adenomas and lymph nodes included the minimum, mean, median and 90^th percentile Hounsfield unit, indicating significant differences in the CT density of the two anatomical structures (Table 1). This is expected given the arterial hyperenhancement of parathyroid adenomas on arterial phase imaging. There are also several second order radiomic features that were significantly different between the two structures, such as entropy (joint entropy and sum entropy) as well as multiple gray level features. These are less well appreciated manually and  Data suggest that parathyroid adenomas have a unique CT textural pattern to help differentiate from lymph nodes. Differing morphological and second order variables can be used in combination to create a texture signature for parathyroid adenomas.