The quality of the reconstruction in terms of noise and sharpness of the kernel was found to be the main factor leading to lower quality of CVD risk estimates. CAC volume generally exhibited a stronger correlation with the corresponding CSCT than Agatston scores, emphasising its reliability in assessing CVD risk. Nonetheless, the strong correlation observed in Agatston scores across various reconstructions of the same scans, and the corresponding high accuracy in estimating CVD risk, provides evidence that quantitative CVD risk assessment based on Agatston scoring can be performed on non-CSCT scans.