The ADC-mean for 6 extremity RMS increased from 1,425±476x10-6mm2/s at baseline (BL) to 1,494±386x10-6mm2/s at presurgical (PS). The ADC-mean for 5 pelvic RMS increased from 1,03±342x10-6mm2/s at BL to 1,677±313x10-6mm2/s at PS. All responders and partial/non-responders presented presurgical RECIST, WHO, and volume stability. At PS, 50% of responders displayed CE-SWI Complete-Ring-pattern (P=0.5578), PWI/DCE Capsular-pattern (P=0.6065), and TIC Type-2 (P=0.6065). First- and High-order Radiomics at PS: No statistically significant differences were observed in ADC or CE-SWI first- or high-order radiomics and PWI/DCE semi-quantitative parameters comparing responders vs. partial/non-responders at PS. Presurgical Model ROC: The model based on the CE-SWI GLSZM Large-Area-High-Gray-Level-Emphasis yielded perfect classification performance (AUC=1.0) in responders vs. partial/non-responders, outperforming ADC-Maximum-2D-Diameter-Slice (0.83), CE-SWI Complete-Ring (AUC=0.67), PWI/DCE Capsular (0.67), RECIST (0.67), and TIC type-2 (0.6).