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Congress: ECR25
Poster Number: C-25325
Type: Poster: EPOS Radiologist (scientific)
DOI: 10.26044/ecr2025/C-25325
Authorblock: O. Muradyan, A. Shirvanyan, A. Abrahamyan; Yerevan/AM
Disclosures:
Olya Muradyan: Nothing to disclose
Ani Shirvanyan: Nothing to disclose
Ani Abrahamyan: Nothing to disclose
Keywords: Abdomen, Oncology, Peritoneum, CT-Quantitative, MR, Localisation, Staging, Statistics, Metastases, Neoplasia
Purpose This study was designed to compare the diagnostic performance of computed tomography (CT) and magnetic resonance imaging (MRI) in the detection of peritoneal carcinomatosis. In particular, the investigation focused on assessing the added diagnostic value of diffusion-weighted imaging (DWI) and T1 out-of-phase sequences, which may enhance lesion conspicuity, improve staging accuracy, and help identify invasion of nearby structures such as the bowel wall.
Read more Methods and materials A prospective analysis was conducted on 50 patients with biopsy-proven peritoneal carcinomatosis. Each patient underwent both CT and MRI examinations within a short interval. The MRI protocol was tailored to include standard sequences along with advanced imaging techniques—specifically DWI and T1 out-of-phase imaging. DWI was utilized for its sensitivity to changes in cellular density and tissue microstructure, while T1 out-of-phase imaging was implemented to improve the detection of lesions within fat-containing regions. Radiologists independently reviewed both imaging modalities for lesion...
Read more Results Among the 50 patients studied, CT and MRI yielded concordant findings in 30 cases, with both modalities demonstrating a similar number and distribution of peritoneal lesions. However, in 15 patients, MRI identified additional lesions or revealed differences in lesion location that were not evident on CT, leading to a reclassification of disease stage. In five patients, lesions were exclusively detected by MRI, having been completely missed on CT. Notably, the combined use of DWI and T1 out-of-phase sequences was crucial...
Read more Conclusion The findings of this study underscore the superior sensitivity of MRI, particularly when incorporating advanced sequences like DWI and T1 out-of-phase imaging, in detecting peritoneal carcinomatosis compared to CT. These techniques provide critical information that can alter disease staging and influence treatment planning, including the identification of local invasion into structures such as the bowel wall. Based on these results, the integration of such MRI sequences into routine clinical protocols is recommended to enhance diagnostic accuracy and optimize patient management...
Read more References 1. Koh, D. M., & Collins, D. J. (2007).Diffusion-weighted MRI in the body: Applications and challenges in oncology.American Journal of Roentgenology, 188(6), 1622–1635.— This review discusses the role of DWI in oncologic imaging, outlining its advantages and challenges in detecting small or subtle lesions, including those in the peritoneum.2. Brakenhoff, R. H., et al. (2009).Imaging of peritoneal carcinomatosis: CT versus MRI.Radiographics, 29(3), 753–762.— This article compares CT and MRI in the evaluation of peritoneal carcinomatosis, highlighting the limitations of CT...
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