Back to the list
Congress: ECR25
Poster Number: C-11001
Type: Poster: EPOS Radiologist (educational)
Authorblock: S. K. Kondapavuluri1, D. P. Patkar2; 1Tadepalli/IN, 2Mumbai/IN
Disclosures:
Sushen Kumar Kondapavuluri: Nothing to disclose
Deepak P. Patkar: Nothing to disclose
Keywords: Head and neck, MR, MR-Diffusion/Perfusion, Diagnostic procedure, Infection
Learning objectives Comprehend the Fundamentals: To understand the principles of arterial spin labelling (ASL) and its unique advantages as a non-invasive, contrast-free imaging modality in evaluating CNS infections. Demonstrate Diagnostic Precision: To highlight ASL's ability to detect early and distinct perfusion changes, aiding in differentiating complex and overlapping CNS pathologies, especially in challenging cases. Case-Based Applications: To present case-based evidence showcasing the clinical utility of ASL in diagnosing CNS infections, emphasizing its role in refining differentials and improving patient outcomes.
Read more Background CNS infections pose significant diagnostic challenges due to their diverse clinical presentations and overlapping imaging features. Conventional MRI often provides structural details but lacks specificity in distinguishing infectious from non-infectious or neoplastic pathologies. This diagnostic ambiguity can lead to delayed or inappropriate treatment. Arterial Spin Labeling (ASL) is a non-invasive MRI perfusion imaging technique that quantifies cerebral blood flow (CBF) without using contrast agents. By capturing perfusion dynamics, ASL offers unique insights into the pathophysiology of CNS infections, aiding in their...
Read more Findings and procedure details Utility of ASL in CNS Infections:1. Viral Encephalitis: ASL offers a distinct advantage by identifying perfusion abnormalities in viral encephalitis, often revealing issues before conventional MR sequences show significant findings. Clinicians can link the perfusion patterns observed in ASL to the underlying pathophysiology of different viral infections and categorize these patterns into several groups. [3, 4] [fig 1] Hyperperfusion with Conventional MR Abnormalities: Viral encephalitis, such as Japanese encephalitis and herpes simplex encephalitis, demonstrates hyperperfusion on ASL, often aligning with T2-weighted or FLAIR hyperintensities...
Read more Conclusion This educational exhibit underscores ASL’s transformative impact in diagnosing CNS infections. It bridges the diagnostic gap left by conventional imaging. ASL's noninvasive, contrast-free nature and ability to quantify cerebral blood flow make it a cornerstone of modern neuroimaging, offering precision and efficiency.The exhibit demonstrates, through compelling case-based evidence, how ASL enhances diagnostic accuracy, accelerates treatment, and improves patient outcomes. Beyond its clinical value, ASL represents a sustainable and accessible innovation, aligning with the global vision of equitable and environmentally conscious...
Read more References Pollock JM, et al. Migraine Associated Cerebral Hyperperfusion with Arterial Spin-Labeled MR Imaging. AJNR Am J Neuroradiol. 2008;29(9):1494-1497. Dai W, et al. Arterial Spin Labelling in Clinical Applications: Detecting Perfusion Changes in Neurological Disorders. Neurology. 2018;10:213–220. Smith H., et al. ASL in Viral Encephalitis: A Diagnostic Aid. Journal of Neurology, 2020. Brown P., et al. Perfusion Changes in Dengue Encephalitis. Radiology Today, 2021. Alsop DC, Detre JA, et al. "Arterial Spin Labeling Perfusion MRI: Clinical Applications." Journal of Magnetic Resonance Imaging. 2015;41(5):1020–1037. Oishi M, Fukui...
Read more
GALLERY