Genetics associative connections were found between the dilatation of the ducts and the foci of the wems (χ2 = 4.15, p = 0.004), the dilatation of the ducts and the segmental atrophy (χ2 = 10.32, p = 0.001), retraction of the capsule and the foci of the witch (χ2 = 19.55, p = 0.0001), capsule retraction and segmental atrophy (χ2 = 22.57, p <0,0001). According to the received data, there was a dependence of the occurrence of retraction of the capsule and foci of wems with the presence of IDH1/2 mutation (p = 0.042, B = 2.53). There was also the dependence of the appearance of the dilatation of the ducts with the mutation of the gene meter (p = 0.0037, b = 2.74). The fact of the occurrence of a mutation meter (p = 0.014, B1 = 2.88, B2 = 0.22) is associated with a combination of such signs as the dilatation of the ducts and retraction of the capsule. Also the fact of the iDH1/2 mutation (P = 0.004, B1 = 34.7, B2 = –27.6) is associated with a combination of segmental atrophy and foci of wems. The forecast of reckless survival and mortality. We also analyzed the influence of the studied KT-Schools for a five-year risk of relapse and/or death of patients of the icc group. In terms of influence on the risk of relapse and/ or death in patients with icc: p <0.0001, b1 = –3.4, b2 = –3.2 for the pair, the dilatation of the ducts + retraction of the capsule and p = 0.008 b1 = –0.11, b2 = –1.93 for a pair of segmental atrophy/parenchyma hypertrophy + Foci of sowing. The analysis of survival schedules showed the following results. In the presence of bile dilatation The ducts of the median of reckless survival amounted to 15 months, and the share of the surviving patients by the end of the observation period is 27 %. In the absence of dilates the bile ducts of the cumulative share of the survivors at the end of the observation period turned out to be 52 %. Thus, the presence of dilatation of the ducts is reliable It affects the outcome of the outcome in patients with icc (p = 0.0047). Availability on computed tomography (CT) The capsule retraction showed a negative impact during the onset of relapse and/or death (p = 0.027). If the retraction of the median capsule is detected, underlying survival in patients was 18 months. In this case, the share of the patient Entents who survived the 5-year observation period without relapse amounted to 29 %. Patients without retraction of the capsule according to the results of CT noted the best Indicators on this basis: the total share of the survivors was 59 %. Checking the presence or absence of the association of signs was carried out using the exact criterion Fisher. Signs were considered associated at p <0.05.

The development of a tumor of more than 5 cm is not associated with the retraction of the capsule (p = 0.12, χ2 = 2.37). The development of a tumor of more than 5 cm is not associated with the presence of a mutation (p = 0.57, χ2 = 0.32). The discovery of foci is Seva during the CT research was also associated with a negative forecast (p = 0.022). The total share of survivors with a life expectancy of more than 5 years, Which did not find a relapse of the disease in the presence of this feature, turned out to be only 7 %. At the same time, the median of reckless survival was 15 months. If, according to the results of the CT of the foci of cheaps in the adjacent areas, no, was found, The best results were noted: the proportion of patients with brainstime survival to the end of the observation period was 50 %. Changes in the volume of unchanged parenchyma of the liver also influenced the time before the onset of the studied outcome. The presence of segmental atrophy and/or hypertrophy of parenchyma determined The survival median at the level of 15 months, and the cumulative share of patients with a positive outcome was 13 %by the end of the observation period. Non- For these changes, these changes were accompanied by an increase in the survival median up to 50.5 months, and the lobes of the underlying survival - up to 40 % (p = 0.012) When analyzing the influence of pair of CT signs, the following patterns were revealed for the time to the studied outcome. The simultaneous presence in the patient’s dilatation of the bile ducts and retraction of the capsule demonstrated statistically more a  low total fraction of the survivors without relapse by the end of the observation period compared to the group of patients without simultaneous duct dilatation and capsule retraction (0.06 ± 0.06 versus 0.71 ± 0.08, p = 0.0001). In turn, the simultaneous determination in the patient of the foci of wems in the liver and segmental atrophy/hypertrophy of the parenchyma was also accompanied by a statistically significant difference in time before the study studied: a group of patients with both CT signs had a share of 0.11 ± 0.06 survivors to the end of the study, Without these signs or only with one of them-0.54 ± 0.05 (p = 0.005). The second stage in each patient was evaluated by a CT-picture of the lesion of the lesion with the definition of such generally accepted indicators as localization, educational measures, contours of education, the presence of an extraorgan component, the nature of the growth of education, invasion into the surrounding tissues, the nature of the con- Training, an increase in regional lymph nodes. In addition to these parameters, we focused on identifying the following CT signs: the dilatation of the bile ducts, the presence or absence of retraction of the capsule, finding the foci Walking in adjacent areas and a change in tissue volume in the form of segmental atrophy or hypertrophy of parenchyma. Thus, dilatation of the bile ducts Statistically significantly more often detected in the ICC group compared to groups of hepatocellular carcinoma and metastases. As for the presence Retraction of the capsule, ICC groups and hepatocell carcinomas statistically did not differ in this indicator, but in patients with metastases in the liver this parameter was observed Less commonly compared to the ICC group. A similar picture was also formed in relation to the foci of wems: the involvement in the pathological process of the adjacent regions was statistically significantly more often found in patients with ICC. However, changes tissue volumes (segmental atrophy/parenchyma hypertrophy) was more often detected in patients with hepatocellular carcinoma compared to patients in the ICC group.