Congress:
ECR25
Poster Number:
C-13574
Type:
Poster: EPOS Radiologist (scientific)
Authorblock:
R. Mohan, R. Misra, N. Bagri; New Delhi/IN
Disclosures:
Ruchika Mohan:
Nothing to disclose
Ritu Misra:
Nothing to disclose
Neha Bagri:
Nothing to disclose
Keywords:
Genital / Reproductive system female, Oncology, Pelvis, MR, MR-Diffusion/Perfusion, MR-Functional imaging, Diagnostic procedure, Radiation therapy / Oncology, Cancer
- Findings regarding quantitative MRI perfusion parameters can be explained on the basis of the microstructural dynamics of tumor. More aggressive tumors are characterized by higher cellular density, resulting in lower Ktrans and Ve which represent reduced transport of contrast media from blood vessels into the extra-cellular extravascular space (EES) and reduced volume of actual extracellular space into which the contrast will leak from the capillaries. The present study results show that quantitative perfusion dependent parameters (Ktrans & Ve) have a higher value in low grade, stage and endometrioid type of tumor.
- Quantitative diffusion and perfusion MRI parameters have a significant role in the characterization of endometrial carcinoma in terms of likely histological Type of Tumor (Endometroid vs Non Endometroid), Grade of Tumor (Low Grade vs High Grade) and FIGO Stage of Tumor on histopathology. Results of the present study show that MR perfusion can serve as an excellent tool for the prediction of pre-operative aggressiveness of EC.
- Overall, the best perfusion MRI parameter for predicting the histological type and grade of tumor is Ve with diagnostic accuracy of 84% and 87%, respectively, and lower values of Ve are associated with aggressive features of the tumor (Non Endometroid type, high grade, and higher stage of tumor).