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Congress: ECR24
Poster Number: C-11325
Type: EPOS Radiologist (scientific)
Authorblock: D. Saikumar, D. Pio, M. Unni; Thiruvananthapuram/IN
Disclosures:
Dr. Divya Saikumar: Nothing to disclose
Dr. Deepthi Pio: Nothing to disclose
Mr. Madhavan Unni: Nothing to disclose
Keywords: Arteries / Aorta, Eyes, Obstetrics (Pregnancy / birth / postnatal period), Ultrasound-Colour Doppler, Ultrasound-Power Doppler, Ultrasound-Spectral Doppler, Outcomes analysis, Haemodynamics / Flow dynamics, Hypertension, Obstetrics
Purpose The main objective of this study is to examine the potential value of maternal Ophthalmic artery Doppler parameters at 18-24 weeks of gestation in the prediction of subsequent development of Pre-eclampsia.
Read more Methods and materials BACKGROUND Pre-eclampsia (PE) is a pregnancy related hypertensive disorder occuring usually after 20 weeks of gestational age that may progress to eclampsia, which is the end point of the disease spectrum if left untreated [1]. This disease affects 2-8% of all pregnancies and is a major cause of maternal and perinatal morbidity and mortality [2]. Prediction of PE during the second trimester of pregnancy will help in the prompt identification of high risk pregnant women. When these women are provided with adequate prenatal...
Read more Results Study participantsOut of the study population of 408 pregnant ladies who were followed up till 2 weeks after delivery, 15 developed PE (3.6 %). Maternal and demographic characteristics of the study population are summarized in the following table. [fig 6] Outcome All the independent variables (UtPI, PI, PSV1, PSV2, PSV ratio) except MAP were normally distributed. The difference in means of each independent variable in women with PE versus normal were calculated using Students T-test. This difference was found to be statistically significant for MAP...
Read more Conclusion Maternal ophthalmic artery mean PSV ratio was found to be a statistically significant independent predictive marker for the subsequent development of Pre-eclampsia.  Ophthalmic artery mean PSV ratio was found to have a higher sensitivity than uterine artery pulsatility index, which is currently used as one of the biomarkers in the prediction of Pre-eclampsia. Rest of the ophthalmic artery Doppler parameters like PI and mean PSV2 were found to have a univariate association with the outcome of developing Pre-eclampsia. However further studies in different...
Read more References Osungbade KO, Ige OK. Public health perspectives of pre-eclampsia in developing countries : implication for health system strengthening. J Pregnancy 2011;2001:491095. Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet 2005; 365 : 785-799. Young BC, Levine RJ, Karumanchi SA. Pathogenesis of preeclampsia. Annu Rev Pathol 2010; 5 : 173-192. Diniz AL, Moron AF, dos Santos MC, N Sass, CR Pires, CL Debs. Ophthalmic artery Doppler as a measure of severe pre-eclampsia. Int J Gynaecol Obstet 2008; 100 : 216-220. Olatunji RB, Adekanmi AJ, Obajimi...
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