Back to the list
Congress: ECR24
Poster Number: C-13705
Type: EPOS Radiologist (scientific)
Authorblock: T. N. Tulsani, A. A. Patil; Kolhapur/IN
Disclosures:
Tamanna Navin Tulsani: Nothing to disclose
Ashish Anandrao Patil: Nothing to disclose
Keywords: Musculoskeletal spine, Neuroradiology spine, MR, Comparative studies, Biological effects, Tissue characterisation
Purpose The study aims to compare the technique of quantitative T2 mapping with qualitative Pfirrmann grading and also to explore the feasibility and value of quantitative evaluation techniques like T2 mapping in early detection of Lumbar disc degeneration. 
Read more Methods and materials BACKGROUND:Low back pain is a leading cause of disability worldwide with intervertebral disc degeneration (IVDD) being one of its major causes.IVDD is progressive and irreversible structural failure of the disc's compartments that results in biomechanical dysfunction. The early changes in IVDD are primarily associated with the loss of proteoglycan content in the nucleus pulposus (NP) and reduction in the water binding capacity; eventually leading to loss of hydration and osmotic pressure.Magnetic resonance imaging (MRI) is the most widely used method...
Read more Results 100 patients presenting with complaint of low back pain were examined, of which 49 patients were male and 51 female (figure 5).A total of 494 discs were examined of 100 patients, 5 discs from each patient from L1-L2 to L5-S1. Sacralisation of L5 vertebral body was noted in 6 patients. According to the Pfirrmann grading system, 70 discs (14%) were classified as grade I, 130 discs (26%) as grade II, 134 discs (27%) as grade III, 145 discs (30%) as grade IV...
Read more Conclusion In the current scenario, with emerging treatment strategies being developed for the management of disc degeneration, quantitative techniques that evaluate the changes in the water and proteoglycan content of the disc become essential. MRI T2 mapping is a non-invasive quantitative evaluation method that offers high reproducibility.This study provides detailed data about T2 relaxation times, at 3.0 T, in lumbar intervertebral discs at different stages of degeneration and provides with the baseline normative data on T2 values for Indian population at...
Read more References Shetty GM, Jain S, Thakur H, Khanna K. Prevalence of low back pain in India: A systematic review and meta-analysis. Work. 2022 Aug 6;1–24. Cassinelli EH, Hall RA, Kang JD. Biochemistry of intervertebral disc degeneration and the potential for gene therapy applications. The Spine Journal. 2001 May;1(3):205–14. Stelzeneder D, Welsch GH, Balázs Kovács, Goed S, Tatjana Paternostro-Sluga, Vlychou M, et al. Quantitative T2 evaluation at 3.0 T compared to morphological grading of the lumbar intervertebral disc: A standardized evaluation approach in patients with low back pain....
Read more
GALLERY