In the present study, ten different thrombus types were created and analysed using SDCT. The conventional images showed a higher RBC content with a higher conventional CT density, and it was possible to differentiate the thrombi based on the conventional HU values (p<0.001) [Fig. 2]. Spectral analysis of the ED also demonstrated a positive correlation between the RBC content and the ED values, which enabled differentiation of the thrombus types (p<0.001) [Fig. 3]. In contrast, the analysis of the Zeff values did not show any correlation with the RBC content and therefore did not allow a differentiation of the thrombus types. In the analysis of the MonoE maps, all thrombus types had the highest HU values in the MonoE 40 keV map and the lowest HU values in the MonoE 200 keV map. Along the keV spectrum, the thrombi showed similar dynamics of HU values. Although the absolute HU drop from 40 keV to 200 keV did not differ between the thrombus types [Fig. 4], the relative drop in thrombi with higher RBC content was lower than in those with lower RBC content (p < 0.001) [Fig. 5].