Endometriosis is a chronic gynecological disease characterized by the presence of endometrial tissue outside the uterus, causing pelvic pain and infertility [1]. Lesions can appear in various locations, most commonly affecting the ovaries, followed by the posterior broad ligament, the anterior cul-de-sac, the posterior cul-de-sac and the uterosacral ligament [2]. The clinical manifestation of the disease varies among women and can be unpredictable in both its presentation and duration. The disease in females typically manifests with symptoms such as dyspareunia (painful sexual intercourse), pelvic pain during menstruation (dysmenorrhea), pain during urination (dysuria) or during defecation (dyschezia), or infertility [3]. The pain is often described as chronic, cyclic, and progressively worsening over time [4]. The macroscopic appearances of the disease includes three different types:
• Endometriomas (also known as endometriotic cysts or "chocolate cysts") [5] typically form in the ovaries as a result of repeated cyclic bleeding in a deep implant. This often leads to the complete replacement of ovarian tissue. The cyst walls may thicken and become fibrous, accompanied by strong adhesions, while the lining can vary in appearance (from smooth to irregular) and color (usually pale-to-brown) [6];
• Small superficial peritoneal implants: a condition known as “Sampson syndrome,” characterized by multiple superficial plaques or nodules of different sizes, ranging from a few millimeters to 2 cm in diameter, scattered across the peritoneum and pelvic ligaments [7];
• Deep infiltrating endometriosis occurs when lesions extend into the retroperitoneal area or the walls of pelvic organs to a depth of at least 5 mm, including nodules, cysts, and secondary scarring [8].
Our study aims to determine the prevalence of a retroverted-flexed uterus in women with endometriosis and, among women with a retroverted-flexed uterus, to identify those with diagnosed endometriosis, newly diagnosed cases, and those where the finding was due to another causes.