A retrospective analysis was conducted on preoperative spectral CT images, clinical, and pathological data of 88 patients who underwent radical resection for HCC between 2018 and 2022, categorized into an ER group (n=37) and a non-ER group (n=51). Histogram parameters of the whole tumor were calculated from iodine (water) maps derived from the portal venous phase of spectral CT, including Min, Max, Mean, SD, Variance, Skewness, Kurtosis, Entropy, and percentiles (V10-V95). Multivariate logistic regression analysis was used to assess the predictive factors for NRM-HCC with varying recurrence outcomes, and a comprehensive model was developed. The performance of the comprehensive model was evaluated using receiver operating characteristic (ROC) analysis, calibration curves, and clinical decision curves (DCA).