High-frequency ultrasound (US) transducers are increasingly being integrated into clinical practice due to their ability to provide high-resolution imaging of millimetric and superficial anatomical structures. Their enhanced spatial resolution makes them particularly useful for evaluating delicate tissues, fine vascular networks, and small pathological changes that may not be as clearly visualized with conventional ultrasound probes [1, 2].

Despite these advantages, there is currently limited research on their specific application in assessing the retroareolar-nipple region, a complex anatomical area characterized by intricate ductal and glandular structures. Imaging this region presents several challenges, primarily due to potential distortion and shadowing artifacts, which can obscure critical diagnostic details. Given the clinical importance of accurately assessing retroareolar findings—especially in cases involving suspected pathology such as ductal ectasia, papillomas, or early malignancies—there is a pressing need for comparative studies evaluating the effectiveness of different ultrasound probes in this context [3, 4].

This single-center study aims to address this gap by directly comparing the diagnostic performance of a classic linear probe (CLP) versus a high-frequency probe (HFP) in detecting and characterizing retroareolar abnormalities. By assessing image quality, lesion detectability, and diagnostic accuracy, this study seeks to determine whether the superior resolution of high-frequency ultrasound offers a significant advantage over conventional probes in visualizing this anatomically and diagnostically challenging region.