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Congress: ECR25
Poster Number: C-18242
Type: Poster: EPOS Radiographer (educational)
Authorblock: W. McGuire1, M. Fennessy1, K. Thakor1, D. Nickel2, E. Weiland2, A. R. R. Padhani1; 1Northwood/UK, 2Forchheim/DE
Disclosures:
Will McGuire: Nothing to disclose
Marie Fennessy: Nothing to disclose
Kirti Thakor: Nothing to disclose
Dominik Nickel: Employee: Siemens Healthineers
Elisabeth Weiland: Employee: Siemens Healthineers
Anwar R. R Padhani: Advisory Board: Siemens Healthineers Speaker: Siemens Healthineers Research/Grant Support: Siemens Healthineers
Keywords: Bones, Oncology, Radiographers, MR, Diagnostic procedure, Imaging sequences, Radiation therapy / Oncology, Cancer, Metastases
Conclusion

We have demonstrated two practical MRI methods for generating BW-CT-like images that provide diagnostic-quality visualisation of the mineralised bone matrix. In some patients, DL VIBE sequences enhanced the conspicuity of lytic bone deposits compared to BW-CT. Fusing diffusion weighted images with a b-value of 900 s/mm2 (b900) and DL VIBE sequences further improved lesion conspicuity.

 

Free-breathing DL VIBE produces sharp BW-CT-like images with good SNR and comparable resolution. While further optimisation of acquisition time is needed, it appears best suited for region-specific imaging.

 

When combined with time-efficient DL-enhanced diffusion-weighted imaging, whole-body range breath-hold DL VIBE can be incorporated as an additional sequence in WB-MRI without extending the total examination time.

 

The combination of pseudo-CT images with b900 images enables the detection of a potentially new bone metastasis phenotype (b900(+)PseudoCT(-)), and its prognostic significance is currently under investigation.

 
GALLERY