The prevalence of steatotic liver disease worldwide is high, therefore a non-invasive and cost-effective tool to accurately detect individuals with liver steatosis is needed. iATT algorithm implemented in Arietta series ultrasound systems (Fujifilm, Tokyo, Japan) estimates attenuation coefficient (AC) for fat quantification in a fixed region of interest (ROI) from 35 to 75mm from the transducer. The fixed ROI distance can be a limitation for individuals with thick subcutaneous tissue, i.e., overweight or obese.
Aims: To evaluate whether correlation between AC and magnetic resonance imaging proton density fat fraction (MRI-PDFF) and performance could improve by (i) reducing ROI length to 30mm, while the starting point is 45mm from the transducer; (ii) using floating ROI for measurements at different depths.