Case 1
The first case is an 87-year-old woman with grade II invasive ductal carcinoma refractory to hormone therapy scandidate for microwave ablation. (Fig. 8).
On the one month follow-up mammography an inflammatory halo is observed, which corresponds to the necrosis of the tumor's fat. This finding is confirmed on the additional ultrasound study, where we can see a nodule with poorly defined margins and hyperechogenicity of the adjacent fat. On the 3-month follow-up mammography the previously described findings become more evident. On de ultrasound study we can now observe patchy hypoechoic areas. On the one-year follow-up these findings become more pronounced. Two years after the thermal ablation, the area of fat necrosis has reduced in size and the functional study (contrast-enhanced mammography) confirms the absence of lesion uptake. (Fig. 9).
Case 2
91-year-old woman with a two-month history palpable nodule in the left breast. The diagnostic mammography shows a nodule in the upper outer quadrant of the left breast, which is confirmed by ultrasound (Fig. 10). After biopsy, the histological result is encapsulated papillary neoplasm. Due to the high surgical risk, the treatment of choice is microwave ablation.
Since the nodule is very close to the skin, we performed hydrodissection to reduce the risk of skin burn. On the 6-month follow-up after ablation an inflammatory halo is observed on the mammography, which corresponds to the necrosis of the tumor's fat. (Fig. 11)
Case 3
91-year-old woman. Mammography reveals focal asymmetry in the right breast. (Fig.12) A biopsy is performed and the result is Luminal A ductal carcinoma. It is decided to treat with microwave ablation. One-month after the ablation, an inflammatory halo is observed on the mammography, which corresponds to the necrosis of the tumor's fat. This finding is confirmed on the additional ultrasound study. (Fig. 13) One year after the procedure, on the contrast-enhanced mammography and ultrasound, a residual tumor is seen within the area of fat necrosis. (Fig. 14) The patient is a candidate for a new ablation session. At the six-month follow-up after the second microwave ablation session, no tumor remnant remains. (Fig. 15).