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Congress: ECR25
Poster Number: C-20239
Type: Poster: EPOS Radiologist (scientific)
Authorblock: J. Lee, S-Y. Choi, N. Y. Han, J. H. Kim, J. E. Lee; Seoul/KR
Disclosures:
Jisun Lee: Nothing to disclose
Seo-Youn Choi: Nothing to disclose
Na Yeon Han: Nothing to disclose
Jung Hoon Kim: Nothing to disclose
Ji Eun Lee: Nothing to disclose
Keywords: Abdomen, CT, Computer Applications-General, Neoplasia
Purpose The primary aim of the present study was to assess the interobserver agreement among experienced radiologists who have completed an abdominal fellowship and radiology residents from four medical centers in predicting the malignant potential of pancreatic IPMNs using CT in conjunction with the revised 2017 IAP guidelines. We also sought to evaluate the diagnostic performance of CT for identifying malignant IPMNs based on the reviewers’ experience, focusing on the challenge of enhancing diagnostic consistency and accuracy.
Read more Methods and materials Study Population and Image AnalysisThe present multicenter retrospective study included 120 patients with pathologically confirmed pancreatic IPMN who underwent CT between 2010 and 2023. Eight reviewers – four abdominal radiologists and four radiology residents – interpreted the CT images, and diagnostic performance and interobserver agreement were analyzed using Fleiss κ statistics and receiver operating characteristic analysis, based on both the IAP guidelines and the reviewers’ experience.For each of the 120 patients, the radiologists evaluated the following parameters related to IPMNs...
Read more Results Patient DemographicsA total of 120 patients with IPMNs (mean age, 65.90 years ± 10.49 [standard deviation]) were included in our study, of whom 67 (55.83%) had benign IPMNs, while 53 (44.16%) had malignant IPMNs (22 (18.33%). (Table 2). The mean interval between CT examination and surgery or biopsy was 31 days (range, 1–80 days). Of the 120 patients, 104 (86.67%) underwent surgery and 16 (13.33%) underwent endoscopic US-guided biopsy. All 16 patients with US-confirmed IPMNs had high-grade dysplasia or invasive...
Read more Conclusion The 2017 IAP guidelines showed good diagnostic performance and moderate interobserver agreement for evaluating the malignant potential of pancreatic IPMNs on CT, with both being higher among the more experienced reviewers. The 2017 IAP guidelines enhanced the diagnostic performance and interobserver agreement of the less experienced reviewers.
Read more References References Bosman FT. WHO classification of tumours of the digestive system. Lyon: IARC Press, 2010. Lim JH, Lee G, Oh YL. Radiologic spectrum of intraductal papillary mucinous tumor of the pancreas. Radiographics 2001;21(2):323-337; discussion 337-340. doi: 10.1148/radiographics.21.2.g01mr01323. Nagtegaal ID, Odze RD, Klimstra D, Paradis V, Rugge M, Schirmacher P, Washington KM, Carneiro F, Cree IA, WHO Classification of Tumours Editorial Board. The 2019 WHO classification of tumours of the digestive system. Histopathology 2020;76(2):182–188. doi: 10.1111/his.13975. Megibow AJ, Baker ME, Morgan DE, Kamel IR, Sahani...
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