The primary objective of this scientific exhibit is to provide an in-depth radiologic journey through the complex architecture of cerebral white matter. By leveraging advanced Diffusion Tensor Imaging (DTI) and tractography, this work seeks to:
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Elucidate the physical, mathematical, and technical foundations of DTI, from the concept of Brownian motion to the generation of the diffusion tensor.
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Detailed the methodology behind tractography reconstruction, including seed placement, tracking algorithms (deterministic vs. probabilistic), and the importance of region-of-interest (ROI) selection.
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Provide a systematic, step-by-step anatomical mapping of the brain’s "bridges," categorized into association, commissural, and projection fibers, following a strict neuroanatomical and radiologic correlation.
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Correlate historical neuroanatomical milestones with modern clinical cases, such as "Sacre Bleu" (Baudelaire) and Phineas Gage, to illustrate the impact of white matter disconnection syndromes.
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Demonstrate the clinical relevance of tractography in preoperative planning, particularly in the preservation of eloquent pathways during neurosurgical interventions.