As Thomas Willis intuited centuries ago, the brain’s function is not found in its hollow spaces but in its structural connections. The transition from the anecdotal clinical observations of Baudelaire’s "Sacre Bleu" or Phineas Gage’s personality shift to modern, color-coded DTI maps represents one of the greatest leaps in neuro-radiology.

Tractography, through the careful selection of seeds and tracking parameters, transforms MRI from a static anatomical picture into a dynamic map of the mind’s "bridges." For the modern radiologist and neurosurgeon, understanding this white matter landscape is no longer optional; it is the key to preserving the essence of the patient while treating the pathology. By utilizing these radiologic lenses, we ensure that while we treat the "cities" of the brain, we do not destroy the "bridges" that allow them to communicate.